Hamaji Masatsugu, Ali Syed Osman, Burt Bryan M
Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan.
Division of Cardiothoracic Surgery, Altru Hospital, Grand Forks, North Dakota.
Ann Thorac Surg. 2014 Aug;98(2):748-55. doi: 10.1016/j.athoracsur.2014.04.028. Epub 2014 Jun 28.
This meta-analysis was designed to determine the effect of surgical and nonsurgical approaches on 5-year and 10-year overall survival (OS) in patients with recurrent thymoma. PubMed, Scopus, and the Journal of Japanese Association for Chest Surgery were queried, and 11 studies were eligible. Our meta-analysis using a random-effect model revealed significant differences in the rates of 5- and 10-year OS after thymectomy and in 5-year OS after recurrence, favoring surgically managed patients. Surgical resection may be associated with improved long-term survival and should be considered for patients with recurrent thymoma.
本荟萃分析旨在确定手术和非手术方法对复发性胸腺瘤患者5年和10年总生存率（OS）的影响。检索了PubMed、Scopus和《日本胸部外科学会杂志》，共有11项研究符合条件。我们使用随机效应模型进行的荟萃分析显示，胸腺切除术后5年和10年总生存率以及复发后5年总生存率存在显著差异，手术治疗的患者更具优势。手术切除可能与长期生存率提高相关，复发性胸腺瘤患者应考虑手术治疗。
