Dancer B N, Power E G, Russell A D
School of Pure and Applied Biology, University of Wales College of Cardiff, U.K.
FEMS Microbiol Lett. 1989 Feb;57(3):345-8. doi: 10.1016/0378-1097(89)90326-1.
Spores of Bacillus subtilis 168 were apparently fully inactivated by exposure to 2% (w/v) glutaraldehyde for 20 h but a few spores could be revived by further treatment with 10-100 mM NaOH. A similar effect was found with spores from a range of Bacillus species. A minimum concentration of 5% (w/v) glutaraldehyde was required to prevent the alkali-induced reactivation. The implications of these results for the use of glutaraldehyde as a sporicidal agent are discussed.
枯草芽孢杆菌168的孢子在2%（w/v）戊二醛中暴露20小时后显然已完全失活，但用10 - 100 mM氢氧化钠进一步处理后，仍有少数孢子能够复苏。一系列芽孢杆菌属的孢子也发现了类似的效果。需要至少5%（w/v）的戊二醛浓度才能防止碱诱导的再活化。本文讨论了这些结果对戊二醛作为杀孢子剂使用的影响。
