来自阿尔及利亚的多重耐药性大肠埃希菌临床分离株中的NDM-5碳青霉烯酶编码基因。
NDM-5 carbapenemase-encoding gene in multidrug-resistant clinical isolates of Escherichia coli from Algeria.
作者信息
Sassi Asma, Loucif Lotfi, Gupta Sushim Kumar, Dekhil Mazouz, Chettibi Houria, Rolain Jean-Marc
机构信息
Unité de Recherche sur les Maladies Infectieuses et Tropicales Émergentes (URMITE), UMR CNRS, IHU Méditerranée Infection, Faculté de Médecine et de Pharmacie, Aix-Marseille-Université, Marseille, France Département de Biochimie, Faculté des Sciences, Université Badji Mokhtar, Annaba, Algeria Laboratoire Central de Microbiologie, CHU Annaba, Annaba, Algeria.
Unité de Recherche sur les Maladies Infectieuses et Tropicales Émergentes (URMITE), UMR CNRS, IHU Méditerranée Infection, Faculté de Médecine et de Pharmacie, Aix-Marseille-Université, Marseille, France Département de Biochimie, Faculté des Sciences, Université Badji Mokhtar, Annaba, Algeria.
出版信息
Antimicrob Agents Chemother. 2014 Sep;58(9):5606-8. doi: 10.1128/AAC.02818-13. Epub 2014 Jun 30.
Abstract
Here, we report the first autochthonous cases of infections caused by blaNDM-5 New Delhi metallo-β-lactamase-producing Escherichia coli strains recovered from urine and blood specimens of three patients from Algeria between January 2012 and February 2013. The three isolates belong to sequence type 2659 and they coexpress blaCTX-M-15 with the blaTEM-1 and blaaadA2 genes.
摘要
在此，我们报告了2012年1月至2013年2月期间从三名阿尔及利亚患者的尿液和血液标本中分离出的产blaNDM - 5新德里金属β-内酰胺酶的大肠杆菌菌株引起的首例本地感染病例。这三株分离菌属于序列型2659，它们与blaTEM - 1和blaaadA2基因共表达blaCTX - M - 15。
相似文献
1
NDM-5 carbapenemase-encoding gene in multidrug-resistant clinical isolates of Escherichia coli from Algeria.
Antimicrob Agents Chemother. 2014 Sep;58(9):5606-8. doi: 10.1128/AAC.02818-13. Epub 2014 Jun 30.
2
Prevalence of Extended-Spectrum Beta-Lactamase and Carbapenemase Genes in Clinical Isolates of Escherichia coli in Myanmar: Dominance of bla and Emergence of bla.
Microb Drug Resist. 2018 Nov;24(9):1333-1344. doi: 10.1089/mdr.2017.0387. Epub 2018 Mar 22.
3
Novel variant NDM-11 and other NDM-1 variants in multidrug-resistant Escherichia coli from South India.
J Glob Antimicrob Resist. 2018 Sep;14:154-157. doi: 10.1016/j.jgar.2018.04.001. Epub 2018 Apr 12.
4
Plasmid analysis of Escherichia coli isolates from South Korea co-producing NDM-5 and OXA-181 carbapenemases.
Plasmid. 2019 Jul;104:102417. doi: 10.1016/j.plasmid.2019.102417. Epub 2019 May 28.
5
Characterization of NDM-7 Carbapenemase-Producing Escherichia coli Isolates in the Arabian Peninsula.
Microb Drug Resist. 2017 Oct;23(7):871-878. doi: 10.1089/mdr.2016.0216. Epub 2017 Feb 3.
6
High frequency of IMP-6 among clinical isolates of metallo-β-lactamase-producing Escherichia coli in Japan.
Antimicrob Agents Chemother. 2012 Aug;56(8):4554-5. doi: 10.1128/AAC.00617-12. Epub 2012 Jun 4.
7
Characterization of carbapenemases, extended spectrum β-lactamases, quinolone resistance and aminoglycoside resistance determinants in carbapenem-non-susceptible Escherichia coli from a teaching hospital in Chongqing, Southwest China.
Infect Genet Evol. 2014 Oct;27:271-6. doi: 10.1016/j.meegid.2014.07.031. Epub 2014 Aug 10.
8
Detection of NDM-7 in Germany, a new variant of the New Delhi metallo-β-lactamase with increased carbapenemase activity.
J Antimicrob Chemother. 2013 Aug;68(8):1737-40. doi: 10.1093/jac/dkt088. Epub 2013 Apr 3.
9
Cross-border emergence of clonal lineages of ST38 Escherichia coli producing the OXA-48-like carbapenemase OXA-244 in Germany and Switzerland.
Int J Antimicrob Agents. 2020 Dec;56(6):106157. doi: 10.1016/j.ijantimicag.2020.106157. Epub 2020 Sep 9.
10
First Detection of New Delhi Metallo-β-Lactamase-5-Producing Escherichia coli from Companion Animals in Korea.
Microb Drug Resist. 2019 Apr;25(3):344-349. doi: 10.1089/mdr.2018.0237. Epub 2018 Oct 31.
引用本文的文献
1
Characterization of -carrying plasmids in two clinical isolates from Jiaxing city, China.
Front Microbiol. 2025 Jun 26;16:1620907. doi: 10.3389/fmicb.2025.1620907. eCollection 2025.
2
Nutritional analysis and characterization of carbapenemase producing-Klebsiella pneumoniae resistant genes associated with bovine mastitis infected cow's milk.
PLoS One. 2023 Oct 27;18(10):e0293477. doi: 10.1371/journal.pone.0293477. eCollection 2023.
3
Review and analysis of the overlapping threats of carbapenem and polymyxin resistant E. coli and Klebsiella in Africa.
Antimicrob Resist Infect Control. 2023 Apr 4;12(1):29. doi: 10.1186/s13756-023-01220-4.
4
Characterization of NDM-5 Carbapenemase-Encoding Gene ( ) - Positive Multidrug Resistant Commensal from Diarrheal Patients.
Infect Drug Resist. 2022 Jul 8;15:3631-3642. doi: 10.2147/IDR.S364526. eCollection 2022.
5
NDM-5-Producing Co-Harboring Gene in Companion Animals in China.
Animals (Basel). 2022 May 20;12(10):1310. doi: 10.3390/ani12101310.
6
First identification of producing from neonates and a HIV infected adult in Tanzania.
J Med Microbiol. 2022 Feb;71(2). doi: 10.1099/jmm.0.001513.
7
Enzyme Inhibitors: The Best Strategy to Tackle Superbug NDM-1 and Its Variants.
Int J Mol Sci. 2021 Dec 24;23(1):197. doi: 10.3390/ijms23010197.
8
Phylogenetic diversity and mutational analysis of New Delhi Metallo-β-lactamase (NDM) producing strains from pediatric patients in Pakistan.
Saudi J Biol Sci. 2021 Oct;28(10):5875-5883. doi: 10.1016/j.sjbs.2021.06.037. Epub 2021 Jun 18.
9
Characterization of a Novel NDM-5-Harboring Plasmid from a Carbapenem-Resistant Isolate from China.
Infect Drug Resist. 2020 Nov 2;13:3929-3935. doi: 10.2147/IDR.S277997. eCollection 2020.
10
Emergence of an NDM-5-Producing Sequence Type 410 Clone in Infants in a Children's Hospital in China.
Infect Drug Resist. 2020 Feb 28;13:703-710. doi: 10.2147/IDR.S244874. eCollection 2020.
本文引用的文献
1
Prevalence of carbapenemase-encoding genes including New Delhi metallo-β-lactamase in Acinetobacter species, Algeria.
Int J Infect Dis. 2013 Sep;17(9):e739-43. doi: 10.1016/j.ijid.2013.02.024. Epub 2013 Apr 16.
2
Dissemination of a class I integron carrying VIM-2 carbapenemase in Pseudomonas aeruginosa clinical isolates from a hospital intensive care unit in Annaba, Algeria.
Antimicrob Agents Chemother. 2013 May;57(5):2426-7. doi: 10.1128/AAC.00032-13. Epub 2013 Mar 4.
3
Identification of New Delhi metallo-β-lactamase 1 in Acinetobacter lwoffii of food animal origin.
PLoS One. 2012;7(5):e37152. doi: 10.1371/journal.pone.0037152. Epub 2012 May 18.
4
Carbapenemase-producing Acinetobacter baumannii in two university hospitals in Algeria.
J Med Microbiol. 2012 Sep;61(Pt 9):1341-1343. doi: 10.1099/jmm.0.045807-0. Epub 2012 May 24.
5
Emergence of blaOXA-23 and blaOXA-58 carbapenemase-encoding genes in multidrug-resistant Acinetobacter baumannii isolates from University Hospital of Annaba, Algeria.
Int J Antimicrob Agents. 2012 Jul;40(1):89-91. doi: 10.1016/j.ijantimicag.2012.03.017. Epub 2012 May 11.
6
Rapid detection of carbapenem resistance in Acinetobacter baumannii using matrix-assisted laser desorption ionization-time of flight mass spectrometry.
PLoS One. 2012;7(2):e31676. doi: 10.1371/journal.pone.0031676. Epub 2012 Feb 16.
7
NDM-1-producing Acinetobacter baumannii from Algeria.
Antimicrob Agents Chemother. 2012 Apr;56(4):2214-5. doi: 10.1128/AAC.05653-11. Epub 2012 Jan 30.
8
A novel variant, NDM-5, of the New Delhi metallo-β-lactamase in a multidrug-resistant Escherichia coli ST648 isolate recovered from a patient in the United Kingdom.
Antimicrob Agents Chemother. 2011 Dec;55(12):5952-4. doi: 10.1128/AAC.05108-11. Epub 2011 Sep 19.
9
Novel VIM metallo-beta-lactamase variant from clinical isolates of Enterobacteriaceae from Algeria.
Antimicrob Agents Chemother. 2010 Jan;54(1):466-70. doi: 10.1128/AAC.00017-09. Epub 2009 Nov 9.
10
Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India.
Antimicrob Agents Chemother. 2009 Dec;53(12):5046-54. doi: 10.1128/AAC.00774-09. Epub 2009 Sep 21.
Zotero 插件