Wanden-Berghe Carmina, Granell Lourdes, Giménez Jose Luis, De Dios Praes Juan, Muñoz-Puller Pedro, Cases Catalina, Santacruz Nieves, González-Valls Teresa
Rev Enferm. 2014 May;37(5):51-4.
The platelet-rich plasma involves a concentration of platelet in a limited volume of plasma. It is used in several tissue regeneration surgical procedures where the growth factor platelet regeneration improves wounds healing.
Describe the treatment effects with platelet-rich plasma in chronic wounds.
Prospective longitudinal study of a series of cases with chronic wounds admitted to the Home Care Unit of the Hospital General Universitario de Alicante. Inclusion criteria were: 1) patients with no infected wounds of any etiology at the time of treatment; 2) informed consent by the patient; 3) monitoring viability.
An extraction of 20 ml of blood was realized. After double centrifugation, the plasma was extracted and the platelets were activated with Calcium chloride. Then we proceeded to the infiltration in the edges and inside the wounds, applying the remaining on the surface. Serial photographs of the injuries were taken, recording their characteristics. As evident improvement criterion was chosen the full certificate of discharge of monitoring of the patient, or controlled by primary attention.
The four treated patients showed a clearly satisfactory evolution, checking clinically a clear improvement of processes with an accelerated healing. Only one of the patients showed an erythema around the injury that resolved spontaneously.
The infiltration of chronic wounds with platelet-rich plasma has been shown as an effective treatment.
富血小板血浆是指在有限体积的血浆中浓缩血小板。它被用于多种组织再生外科手术中，其中血小板再生生长因子可促进伤口愈合。
描述富血小板血浆对慢性伤口的治疗效果。
对阿利坎特大学总医院家庭护理单元收治的一系列慢性伤口病例进行前瞻性纵向研究。纳入标准为：1）治疗时无任何病因的感染伤口患者；2）患者知情同意；3）监测生存能力。
抽取20毫升血液。经过两次离心后，提取血浆并用氯化钙激活血小板。然后我们对伤口边缘和内部进行浸润，将剩余的涂抹在表面。对伤口进行连续拍照，记录其特征。选择患者监测完全出院证明或由初级护理控制作为明显改善标准。
4例接受治疗的患者病情发展明显令人满意，临床检查显示病情明显改善，愈合加速。只有1例患者伤口周围出现红斑，红斑自行消退。
富血小板血浆浸润慢性伤口已被证明是一种有效的治疗方法。
