Ai Zhi-hua, Wan Yong, Liu Jun-jing, Lang Hong-mei, Xiao Jie, Li Ning-na, Cheng Ying, You Zhi-qing
Sichuan Da Xue Xue Bao Yi Xue Ban. 2015 Sep;46(5):770-2.
To evaluate the clinical effectiveness and safety of autologous platelet-rich gel (APG) in the treatment of chronic skin ulcer with tophus.
Four patients of chronic skin ulcer with tophus received routine debridement to remove necrotic tissue and erasion tophus as far as possible,and then received the treatment of APG.
All of the patients had their wounds healed after the treatment of APG (one wound was treated twice). The wounds were healed between 8 to 22 d, average (13. 7±6. 8) d, while there were no adverse effects observed.
Topical therapy with APG may be considered as an effective and safe adjuvant method for the treamtment of chronic skin ulcer with tophus.
评估自体富血小板凝胶（APG）治疗伴有痛风石的慢性皮肤溃疡的临床有效性和安全性。
4例伴有痛风石的慢性皮肤溃疡患者接受常规清创以清除坏死组织并尽可能刮除痛风石，然后接受APG治疗。
所有患者经APG治疗后伤口均愈合（1例伤口治疗2次）。伤口愈合时间为8至22天，平均（13.7±6.8）天，且未观察到不良反应。
APG局部治疗可被视为治疗伴有痛风石的慢性皮肤溃疡的一种有效且安全的辅助方法。
