Wu P C, Yue C T, Huang S C
Eur J Gynaecol Oncol. 2014;35(3):318-21.
The patient presented in this case report was a 45-year-old female, with a Stage IIIA ovarian angiosarcoma combined with mature teratoma, that underwent debulking surgery and achieved complete remission for 11 months after six cycles of MAID chemotherapy (mesna, adriamycin/doxorubicin, ifosfamide, and dacarbazine). Thereafter, she had tumor recurrence with peritoneal seeding and massive pleural effusion; hence she received chemotherapy again. Although she had been undergoing a series of chemotherapies, the tumor continued to progress. Hence, she refused further chemotherapy since September 2012. Unfortunately, she passed away in January 2013 due to severe dyspnea with wide spread tumor progression. She had the longest survival period (31 months) and complete remission period than the other advanced primary ovarian angiosarcoma cases ever reported in the literature.
本病例报告中的患者为一名45岁女性，患有ⅢA期卵巢血管肉瘤合并成熟畸胎瘤，接受了肿瘤细胞减灭术，并在接受六个周期的MAID化疗（美司钠、阿霉素/多柔比星、异环磷酰胺和达卡巴嗪）后实现了11个月的完全缓解。此后，她出现肿瘤复发并伴有腹膜播散和大量胸腔积液；因此她再次接受化疗。尽管她接受了一系列化疗，但肿瘤仍持续进展。因此，自2012年9月起她拒绝进一步化疗。不幸的是，她于2013年1月因广泛肿瘤进展导致的严重呼吸困难而去世。与文献中报道的其他晚期原发性卵巢血管肉瘤病例相比，她的生存期最长（31个月）且完全缓解期最长。
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