Simon S R, Wang S E, Uhl M, Shackney S
Division of Medical Oncology, Allegheny General Hospital, Pittsburgh, Pennsylvania 15212.
Gynecol Oncol. 1991 May;41(2):161-6. doi: 10.1016/0090-8258(91)90278-d.
Although carcinosarcoma occurs in various locations throughout the body, it rarely originates in the ovary. Chemotherapy has been minimally beneficial. This case describes a patient with carcinosarcoma of the ovary who responded minimally to chemotherapy used for epithelial carcinomas but had a complete response after receiving chemotherapy used for sarcomas. The patient relapsed within 1 year after receiving cisplatin therapy. She was treated with mesna, ifosfamide, Adriamycin, and dacarbazine (MAID) chemotherapy and after one cycle of chemotherapy she had no evidence of tumor. She has received six cycles of chemotherapy without evidence of progression 13+ months since beginning MAID therapy. MAID chemotherapy may be useful in the treatment of carcinosarcoma of the ovary.
尽管癌肉瘤可发生于全身各处，但极少起源于卵巢。化疗的益处极小。本病例描述了一名卵巢癌肉瘤患者，其对上皮癌所用化疗反应极小，但在接受肉瘤所用化疗后完全缓解。该患者在接受顺铂治疗后1年内复发。她接受了美司钠、异环磷酰胺、阿霉素和达卡巴嗪（MAID）化疗，化疗一个周期后未见肿瘤迹象。自开始MAID治疗以来，她已接受六个周期化疗，13个多月来无疾病进展迹象。MAID化疗可能对卵巢癌肉瘤的治疗有用。
