Aurégan Jean-Charles, Bégué Thierry
Department of Orthopaedic, Trauma and Reconstructive Surgery, Antoine Béclère Hospital, AP-HP, Paris Sud University, 157 rue de la Porte de Trivaux, 92140, Clamart, France,
Int Orthop. 2014 Sep;38(9):1971-8. doi: 10.1007/s00264-014-2422-y. Epub 2014 Jul 2.
The purpose of this study was to review experimental and clinical experiences about the use of an induced membrane to address critical bone size defect of the limbs.
From a review of published experimental and clinical data and from our clinical experience, we present the key data about the use of an induced membrane to address critical bone size defect of the limbs.
After reviewing the concept of critical sized bone defect, we present the different indications of an induced membrane, the key points of the surgical technique and the strategy of bone grafting given the indication, localization and importance of the critical sized bone defect. Finally, we discuss the perspective of the use of an induced membrane with various bone substitutes.
The use of an induced membrane to treat critical sized bone defects of the limbs is a simple, reliable and reproducible technique. Certain technical steps should be pointed out and observed with great caution in order to avoid any pitfalls. This technique will probably be a key step for facilitating bone inclusion of new bone substitutes proposed by recent bioengineering.
本研究旨在回顾关于使用诱导膜解决肢体严重骨尺寸缺损的实验和临床经验。
通过回顾已发表的实验和临床数据以及我们的临床经验，我们呈现了关于使用诱导膜解决肢体严重骨尺寸缺损的关键数据。
在回顾了临界尺寸骨缺损的概念后，我们给出了诱导膜的不同适应证、手术技术要点以及根据临界尺寸骨缺损的适应证、部位和重要性进行骨移植的策略。最后，我们讨论了使用诱导膜与各种骨替代物的前景。
使用诱导膜治疗肢体临界尺寸骨缺损是一种简单、可靠且可重复的技术。应特别指出并谨慎遵循某些技术步骤，以避免任何失误。该技术可能是促进近期生物工程提出的新型骨替代物骨融合的关键步骤。
