Birnbaum Andrea D, Rifkin Lana M
Department of Ophthalmology, Northwestern University Feinberg School of Medicine, 645 North Michigan Avenue, Suite 440, Chicago, IL 60611, USA.
J Ophthalmol. 2014;2014:236905. doi: 10.1155/2014/236905. Epub 2014 Jun 2.
Sarcoidosis is an inflammatory disease with a wide range of clinical presentations. The manifestations and prognosis in sarcoidosis are dependent upon not only organ involvement but also age and sex. The purpose of this review is to describe the systemic and ocular manifestations of sarcoidosis with a specific focus on sex-dependent difference in presentation and management. Sarcoidosis is more common in women, particularly in patients who present after age of 50 years. Women with sarcoidosis are more likely to develop cystoid macular edema and the mortality rate is higher than that of men.
结节病是一种临床表现多样的炎症性疾病。结节病的表现和预后不仅取决于器官受累情况,还与年龄和性别有关。本综述的目的是描述结节病的全身和眼部表现,特别关注其在表现和管理方面的性别差异。结节病在女性中更为常见,尤其是在50岁以后发病的患者中。患有结节病的女性更易发生黄斑囊样水肿,且死亡率高于男性。