Zhou Ping-Xin, Ye Yu-Ying, Ma Jun-Wei, Zheng Lan, Tang Qian, Qiu Yi-Feng, Song Bo, Qiu Zi-Hang, Xu Peng-Fei, Liang Yong-Min
State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou 730000, China.
J Org Chem. 2014 Jul 18;79(14):6627-33. doi: 10.1021/jo501125b. Epub 2014 Jul 9.
ortho-Aminated vinylarene derivatives were obtained via a reaction of aryl iodides, N-benzoyloxyamines, and N-tosylhydrazones. This approach involves a palladium-catalyzed, norbornene-mediated ortho-amination/N-tosylhydrazone insertion reaction. In this transformation, one C-N bond and one C-C bond are formed and an amine group is introduced at the ortho position successfully.
通过芳基碘化物、N-苯甲酰氧基胺和N-甲苯磺酰腙的反应得到了邻氨基乙烯基芳烃衍生物。该方法涉及钯催化、降冰片烯介导的邻氨基化/N-甲苯磺酰腙插入反应。在这个转化过程中，形成了一个C-N键和一个C-C键，并成功地在邻位引入了一个胺基。
