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[使用Nalcrom治疗食物过敏患者]

[Treatment of patients with food allergy using Nalcrom].

作者信息

Nogaller A M, Orlov V A, Luniakov A S, Motuzka N P, Petukhova V K

出版信息

Ter Arkh. 1989;61(2):115-8.

PMID:2499073
Abstract

A total of 65 patients with food allergy which manifested primarily by disorders of the gastrointestinal tract, bronchi and skin were placed under observation. The patients were administered sodium chromoglycate (nalcrom) per os in a dose of 200 mg 4 times a day for 2-3 weeks, in part of cases up to 3 months and even up to 1-1.5 year. The skin manifestations of allergy (pruritus, urticaria, Quincke's edema, and eczematous rash), abdominal pain, diarrhea, vomiting, bronchospasm, rhinitis, and conjunctivitis disappeared. At the same time the majority of the patients demonstrated the reduction of the intensity of skin responses to the administration of different food antigens, the decrease of the antibody titer in blood serum in response to food antigens, and of the IgE content in blood. The side effects (nausea, heartburn, intensification of skin itch and abdominal pain) were noted in 4 cases.

摘要

共有65例主要表现为胃肠道、支气管和皮肤紊乱的食物过敏患者接受了观察。患者口服色甘酸钠(咽泰),剂量为每日4次,每次200毫克,持续2 - 3周,部分病例长达3个月,甚至长达1 - 1.5年。过敏的皮肤表现(瘙痒、荨麻疹、昆克水肿和湿疹样皮疹)、腹痛、腹泻、呕吐、支气管痉挛、鼻炎和结膜炎均消失。与此同时,大多数患者对不同食物抗原给药的皮肤反应强度降低,血清中针对食物抗原的抗体滴度以及血液中IgE含量降低。4例出现副作用(恶心、烧心、皮肤瘙痒和腹痛加剧)。

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