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儿童食物过敏与特应性皮炎:口服色甘酸钠治疗

Food allergy and atopic dermatitis in children: treatment with oral sodium cromoglycate.

作者信息

Molkhou P, Waguet J C

出版信息

Ann Allergy. 1981 Sep;47(3):173-5.

PMID:6791532
Abstract

Thirty-five children with atopic dermatitis were proven to be allergic to various foods by dietary elimination and challenge, radio-allergosorbent test (RAST) and human basophil degranulation test (HBDT). Oral sodium cromoglycate improved skin lesions in these patients and protected them from the effects of challenge with food allergens. This protective effect of oral sodium cromoglycate may be explained by the blocking of the immune response in the gut wall and of antigen entry.

摘要

通过饮食排除和激发试验、放射变应原吸附试验(RAST)以及人嗜碱性粒细胞脱粒试验(HBDT),证实35例特应性皮炎患儿对多种食物过敏。口服色甘酸钠可改善这些患儿的皮肤损害,并使其免受食物变应原激发的影响。口服色甘酸钠的这种保护作用可能是由于其阻断了肠壁的免疫反应和抗原进入。

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