Bose Sankhadip, Laha Bibek, Banerjee Subhasis
Department of Pharmacognosy, Gupta College of Technological Sciences, College of Pharmacy, Asansol, West Bengal, India.
Department of Pharmaceutics, Gupta College of Technological Sciences, College of Pharmacy, Asansol, West Bengal, India.
Pharmacogn Mag. 2014 Apr;10(Suppl 2):S288-93. doi: 10.4103/0973-1296.133279.
Garlic (Allium sativum L.) has been accepted universally to be applied in food, spice and traditional medicine. The medicinal and other beneficial properties of garlic are attributed to organosulfur compounds.
As of today no simultaneous analysis has been performed; hence the transformation of allicin to its degraded products during cultivation and storage is open into doubt.
In our present work, we have tried to develop a sensitive and reproducible analytical method to measure allicin by high performance liquid chromatography-ultraviolet analysis with effect of post-acoustic waves and microwave radiation on fresh garlic cloves.
The process revealed the effect of different radiation techniques on fresh garlic retains the principle component, allicin in its pure form and generated higher yield than the conventional way of extraction.
Therefore, materializing these techniques in the pharmaceutical industry will definitely be proved beneficial in term of time as well as money. Most interestingly, the methods ruled out possibilities of degradation of organosulfur compounds as well.
大蒜（葱属植物）已被广泛应用于食品、香料和传统医学领域。大蒜的药用及其他有益特性归因于有机硫化合物。
截至目前，尚未进行同步分析；因此，大蒜素在种植和储存过程中向其降解产物的转化情况仍存在疑问。
在我们目前的工作中，我们试图开发一种灵敏且可重复的分析方法，通过高效液相色谱 - 紫外分析来测定大蒜素，并研究声波和微波辐射对新鲜蒜瓣的影响。
该过程表明不同辐射技术对新鲜大蒜的影响能够保留主要成分——纯形式的大蒜素，且产量高于传统提取方法。
因此，在制药行业实现这些技术在时间和金钱方面肯定会被证明是有益的。最有趣的是，这些方法也排除了有机硫化合物降解的可能性。
