Hall Michael J, Forman Andrea D, Montgomery Susan V, Rainey Kim L, Daly Mary B
Fox Chase Cancer Center, Philadelphia, Pennsylvania.
J Surg Oncol. 2015 Jan;111(1):9-17. doi: 10.1002/jso.23712. Epub 2014 Jul 3.
Advances in genome sequencing technology have fostered a new era of clinical genomic medicine. Genetic counselors, who have begun to support patients undergoing multi-gene panel testing for hereditary cancer risk, will review brief clinical vignettes, and discuss early experiences with clinical genomic testing. Their experiences will frame a discussion about how current testing may challenge patient understanding and expectations toward the evaluation of cancer risk and downstream preventive behaviors.
基因组测序技术的进步开创了临床基因组医学的新时代。遗传咨询师已开始为接受遗传性癌症风险多基因检测的患者提供支持,他们将回顾简短的临床案例,并讨论临床基因组检测的早期经验。他们的经验将引发一场关于当前检测如何可能挑战患者对癌症风险评估和下游预防行为的理解与期望的讨论。