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了解患者和医疗服务提供者对基因组医学的认知与期望。

Understanding patient and provider perceptions and expectations of genomic medicine.

作者信息

Hall Michael J, Forman Andrea D, Montgomery Susan V, Rainey Kim L, Daly Mary B

机构信息

Fox Chase Cancer Center, Philadelphia, Pennsylvania.

出版信息

J Surg Oncol. 2015 Jan;111(1):9-17. doi: 10.1002/jso.23712. Epub 2014 Jul 3.

Abstract

Advances in genome sequencing technology have fostered a new era of clinical genomic medicine. Genetic counselors, who have begun to support patients undergoing multi-gene panel testing for hereditary cancer risk, will review brief clinical vignettes, and discuss early experiences with clinical genomic testing. Their experiences will frame a discussion about how current testing may challenge patient understanding and expectations toward the evaluation of cancer risk and downstream preventive behaviors.

摘要

基因组测序技术的进步开创了临床基因组医学的新时代。遗传咨询师已开始为接受遗传性癌症风险多基因检测的患者提供支持,他们将回顾简短的临床案例,并讨论临床基因组检测的早期经验。他们的经验将引发一场关于当前检测如何可能挑战患者对癌症风险评估和下游预防行为的理解与期望的讨论。

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本文引用的文献

2
Physicians' attitudes about multiplex tumor genomic testing.
J Clin Oncol. 2014 May 1;32(13):1317-23. doi: 10.1200/JCO.2013.52.4298. Epub 2014 Mar 24.
3
Cancer risk assessment using genetic panel testing: considerations for clinical application.
J Genet Couns. 2014 Aug;23(4):604-17. doi: 10.1007/s10897-014-9695-6. Epub 2014 Mar 7.
4
Randomized noninferiority trial of telephone versus in-person genetic counseling for hereditary breast and ovarian cancer.
J Clin Oncol. 2014 Mar 1;32(7):618-26. doi: 10.1200/JCO.2013.51.3226. Epub 2014 Jan 21.
5
Next Generation sequencing is the impetus for the next generation of laboratory-based genetic counselors.
J Genet Couns. 2014 Aug;23(4):647-54. doi: 10.1007/s10897-013-9684-1. Epub 2014 Jan 17.
7
Implementation and outcomes of telephone disclosure of clinical BRCA1/2 test results.
Patient Educ Couns. 2013 Dec;93(3):413-9. doi: 10.1016/j.pec.2013.08.009. Epub 2013 Aug 19.
8
Genomic medicine: too great expectations?
Clin Pharmacol Ther. 2013 Aug;94(2):188-90. doi: 10.1038/clpt.2013.44.
10
ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.
Genet Med. 2013 Jul;15(7):565-74. doi: 10.1038/gim.2013.73. Epub 2013 Jun 20.

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