Laboratoire Interdisciplinaire des Environnements Continentaux (LIEC), Université de Lorraine, UMR 7360 CNRS, Metz, France.
Laboratoire Interdisciplinaire des Environnements Continentaux (LIEC), Université de Lorraine, UMR 7360 CNRS, Metz, France.
Aquat Toxicol. 2014 Oct;155:52-61. doi: 10.1016/j.aquatox.2014.06.008. Epub 2014 Jun 20.
In order to provide reliable information about responsiveness of biomarkers during environmental monitoring, there is a need to improve the understanding of inter-population differences. The present study focused on eight populations of zebra mussels and aimed to describe how variable are biomarkers in different sampling locations. Biomarkers were investigated and summarised through the Integrated Biomarker Response (IBR index). Inter-site differences in IBR index were analysed through comparisons with morphological data, proteomic profiles and genetic background of the studied populations. We found that the IBR index was a good tool to inform about the status of sites. It revealed higher stress in more polluted sites than in cleaner ones. It was neither correlated to proteomic profiles nor to genetic background, suggesting a stronger influence of environment than genes. Meanwhile, morphological traits were related to both environment and genetic background influence. Together these results attest the benefit of using biological tools to better illustrate the status of a population and highlight the need of consider inter-population difference in their baselines.
为了提供有关生物标志物在环境监测过程中反应性的可靠信息，需要提高对种群间差异的认识。本研究集中在八个斑马贻贝种群上，旨在描述不同采样地点的生物标志物有何差异。通过整合生物标志物反应（IBR 指数）研究了生物标志物并对其进行了总结。通过与形态数据、蛋白质组图谱和研究种群的遗传背景进行比较，分析了 IBR 指数的站点间差异。我们发现，IBR 指数是一种很好的工具，可以用来了解站点的状况。它揭示了污染更严重的地点的压力高于污染较轻的地点。它既与蛋白质组图谱无关，也与遗传背景无关，这表明环境的影响比基因更强。同时，形态特征与环境和遗传背景的影响都有关。这些结果共同证明了使用生物工具来更好地说明种群状况的好处，并强调了在确定其基线时需要考虑种群间差异。
