Suppr超能文献

脆性骨折预防指南应用失败。

Failure in the application of fragility fracture prevention guidelines.

作者信息

Elvey M H, Pugh H, Schaller G, Dhotar G, Patel B, Oddy M J

机构信息

University College London Hospitals NHS Foundation Trust, UK.

出版信息

Ann R Coll Surg Engl. 2014 Jul;96(5):381-5. doi: 10.1308/003588414X13946184901164.

Abstract

INTRODUCTION

The cost of fragility fractures to the UK economy is predicted to reach £2.2 billion by 2025. We studied our hip fracture population to establish whether national guidelines on fragility fracture prevention were being followed, and whether high risk patients were identified and treated by local care services.

METHODS

Data on a consecutive series of trauma hip fracture admissions were collected prospectively over 14 months. National Institute for Health and Care Excellence (NICE) and National Osteoporosis Guideline Group (NOGG) recommendations and FRAX(®) risk calculations were applied to patients prior to their admission with a new hip fracture.

RESULTS

Overall, 94 patients were assessed against national guidelines. The mean population age was 77 years. Almost a quarter (22%) of patients had suffered a previous fragility fracture. The mean FRAX(®) ten-year probability of hip fracture was 7%. According to guidelines, 45% of the study population required treatment, 35% fulfilled criteria for investigation and reassessment, and 20% needed no further management. In practice, 27% received treatment, 4% had undergone dual energy x-ray absorptiometry and were untreated, and 69% had not been investigated and were untreated. In patients meeting intervention thresholds, only 33% of those who required treatment were receiving treatment in practice.

CONCLUSIONS

In conjunction with NICE and NOGG recommendations, FRAX(®) was able to identify 80% of our fracture population as intermediate or high risk on the day of fracture. Correct management was evident in a third of cases with a pattern of inferior guideline compliance seen in a London population. There remains a lack of clarity over the duty of care in fragility fracture prevention.

摘要

引言

预计到2025年,脆性骨折给英国经济造成的成本将达到22亿英镑。我们研究了髋部骨折患者群体,以确定是否遵循了国家脆性骨折预防指南,以及当地医疗服务机构是否识别并治疗了高危患者。

方法

前瞻性收集了连续14个月创伤性髋部骨折入院患者的数据。在患者因新发髋部骨折入院前,应用了英国国家卫生与临床优化研究所(NICE)和国家骨质疏松症指南小组(NOGG)的建议以及FRAX(®)风险计算方法。

结果

总体而言,根据国家指南对94例患者进行了评估。患者的平均年龄为77岁。近四分之一(22%)的患者曾发生过脆性骨折。FRAX(®)计算的髋部骨折十年平均概率为7%。根据指南,45%的研究人群需要治疗,35%符合检查和重新评估标准,20%无需进一步处理。在实际情况中,27%的患者接受了治疗,4%接受了双能X线吸收测定但未接受治疗,69%未接受检查且未接受治疗。在达到干预阈值的患者中,实际接受治疗的患者仅占需要治疗患者的33%。

结论

结合NICE和NOGG的建议,FRAX(®)能够在骨折当天将80%的骨折患者识别为中度或高危患者。三分之一的病例管理正确,但伦敦人群中存在指南依从性较差的情况。在脆性骨折预防方面,护理职责仍不明确。

相似文献

1
Failure in the application of fragility fracture prevention guidelines.
Ann R Coll Surg Engl. 2014 Jul;96(5):381-5. doi: 10.1308/003588414X13946184901164.
2
[Application of guidelines for secondary prevention of fracture and the FRAX index in patients with fragility fracture].
Med Clin (Barc). 2011 Mar 19;136(7):290-2. doi: 10.1016/j.medcli.2010.06.028. Epub 2010 Dec 24.
3
A comparison of case-finding strategies in the UK for the management of hip fractures.
Osteoporos Int. 2012 Mar;23(3):907-15. doi: 10.1007/s00198-011-1864-y. Epub 2012 Jan 11.
8
Construction of a FRAX® model for the assessment of fracture probability in Canada and implications for treatment.
Osteoporos Int. 2011 Mar;22(3):817-27. doi: 10.1007/s00198-010-1464-2. Epub 2010 Dec 16.
10
Preoperative bone health assessment and optimization in spine surgery.
Neurosurg Focus. 2020 Aug;49(2):E2. doi: 10.3171/2020.5.FOCUS20255.

引用本文的文献

1
DEXA overestimates bone mineral density in adults with knee replacements.
Sports Med Health Sci. 2020 Nov 4;2(4):211-215. doi: 10.1016/j.smhs.2020.10.002. eCollection 2020 Dec.
5
Optimal use of external demands in hospitals - a Delphi study from the Netherlands.
BMC Health Serv Res. 2016 Feb 20;16:72. doi: 10.1186/s12913-016-1315-8.

本文引用的文献

1
UK health performance: findings of the Global Burden of Disease Study 2010.
Lancet. 2013 Mar 23;381(9871):997-1020. doi: 10.1016/S0140-6736(13)60355-4. Epub 2013 Mar 5.
2
Discrepancies in predicted fracture risk in elderly people.
BMJ. 2013 Jan 21;346:e8669. doi: 10.1136/bmj.e8669.
3
What was your fracture risk evaluated by FRAX® the day before your osteoporotic fracture?
Clin Rheumatol. 2013 Feb;32(2):219-23. doi: 10.1007/s10067-012-2106-1. Epub 2012 Nov 1.
5
Calibration of FRAX ® 3.1 to the Dutch population with data on the epidemiology of hip fractures.
Osteoporos Int. 2012 Mar;23(3):861-9. doi: 10.1007/s00198-011-1852-2. Epub 2011 Nov 26.
6
Fracture prediction and calibration of a Canadian FRAX® tool: a population-based report from CaMos.
Osteoporos Int. 2011 Mar;22(3):829-37. doi: 10.1007/s00198-010-1465-1. Epub 2010 Dec 16.
8
Denosumab for prevention of fractures in postmenopausal women with osteoporosis.
N Engl J Med. 2009 Aug 20;361(8):756-65. doi: 10.1056/NEJMoa0809493. Epub 2009 Aug 11.
9
An estimate of the worldwide prevalence and disability associated with osteoporotic fractures.
Osteoporos Int. 2006 Dec;17(12):1726-33. doi: 10.1007/s00198-006-0172-4. Epub 2006 Sep 16.
10
Assessment of compliance with osteoporosis treatment and its consequences in a managed care population.
Bone. 2006 Jun;38(6):922-8. doi: 10.1016/j.bone.2005.10.022. Epub 2005 Dec 5.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验