Elvey M H, Pugh H, Schaller G, Dhotar G, Patel B, Oddy M J
University College London Hospitals NHS Foundation Trust, UK.
Ann R Coll Surg Engl. 2014 Jul;96(5):381-5. doi: 10.1308/003588414X13946184901164.
The cost of fragility fractures to the UK economy is predicted to reach £2.2 billion by 2025. We studied our hip fracture population to establish whether national guidelines on fragility fracture prevention were being followed, and whether high risk patients were identified and treated by local care services.
Data on a consecutive series of trauma hip fracture admissions were collected prospectively over 14 months. National Institute for Health and Care Excellence (NICE) and National Osteoporosis Guideline Group (NOGG) recommendations and FRAX(®) risk calculations were applied to patients prior to their admission with a new hip fracture.
Overall, 94 patients were assessed against national guidelines. The mean population age was 77 years. Almost a quarter (22%) of patients had suffered a previous fragility fracture. The mean FRAX(®) ten-year probability of hip fracture was 7%. According to guidelines, 45% of the study population required treatment, 35% fulfilled criteria for investigation and reassessment, and 20% needed no further management. In practice, 27% received treatment, 4% had undergone dual energy x-ray absorptiometry and were untreated, and 69% had not been investigated and were untreated. In patients meeting intervention thresholds, only 33% of those who required treatment were receiving treatment in practice.
In conjunction with NICE and NOGG recommendations, FRAX(®) was able to identify 80% of our fracture population as intermediate or high risk on the day of fracture. Correct management was evident in a third of cases with a pattern of inferior guideline compliance seen in a London population. There remains a lack of clarity over the duty of care in fragility fracture prevention.
预计到2025年,脆性骨折给英国经济造成的成本将达到22亿英镑。我们研究了髋部骨折患者群体,以确定是否遵循了国家脆性骨折预防指南,以及当地医疗服务机构是否识别并治疗了高危患者。
前瞻性收集了连续14个月创伤性髋部骨折入院患者的数据。在患者因新发髋部骨折入院前,应用了英国国家卫生与临床优化研究所(NICE)和国家骨质疏松症指南小组(NOGG)的建议以及FRAX(®)风险计算方法。
总体而言,根据国家指南对94例患者进行了评估。患者的平均年龄为77岁。近四分之一(22%)的患者曾发生过脆性骨折。FRAX(®)计算的髋部骨折十年平均概率为7%。根据指南,45%的研究人群需要治疗,35%符合检查和重新评估标准,20%无需进一步处理。在实际情况中,27%的患者接受了治疗,4%接受了双能X线吸收测定但未接受治疗,69%未接受检查且未接受治疗。在达到干预阈值的患者中,实际接受治疗的患者仅占需要治疗患者的33%。
结合NICE和NOGG的建议,FRAX(®)能够在骨折当天将80%的骨折患者识别为中度或高危患者。三分之一的病例管理正确,但伦敦人群中存在指南依从性较差的情况。在脆性骨折预防方面,护理职责仍不明确。