巴戟天（诺丽）提取物对白色念珠菌的抗真菌活性：一项体外研究。
Anti-fungal activity of Morinda citrifolia (noni) extracts against Candida albicans: an in vitro study.
作者信息
Barani K, Manipal Sunayana, Prabu D, Ahmed Adil, Adusumilli Preethi, Jeevika C
机构信息
Department of Public Health Dentistry, SRM Dental College, Ramapuram, Chennai, Tamil Nadu, India.
出版信息
Indian J Dent Res. 2014 Mar-Apr;25(2):188-90. doi: 10.4103/0970-9290.135918.
AIM
The aim of this study was to investigate the anti-fungal activity of Morinda citrifolia fruit extract on Candida albicans.
MATERIALS AND METHODS
Juice extract from M. citrifolia fruit was lyophilized and used in anti-fungal testing. Anti-fungal activity of M. citrifolia fruit extract against C. albicans was tested in vitro at various concentrations. The inhibitory effect of M. citrifolia extract on C. albicans was determined by agar culture and applied broth dilution test.
RESULTS
M. citrifolia extract at 1000 μg/ml concentration effectively inhibited the growth of C. albicans (16.6 ± 0.3) compared with the positive control - amphotericin B (20.6 ± 0.6). It was found to be a dose-dependent reaction.
CONCLUSION
M. citrifolia fruit extract had an anti-fungal effect on C. albicans and the inhibitory effect varied with concentration.
目的
本研究旨在调查海巴戟果实提取物对白色念珠菌的抗真菌活性。
材料与方法
将海巴戟果实的汁液提取物冻干后用于抗真菌测试。在体外以不同浓度测试海巴戟果实提取物对白色念珠菌的抗真菌活性。通过琼脂培养和应用肉汤稀释试验来确定海巴戟提取物对白色念珠菌的抑制作用。
结果
与阳性对照两性霉素B（20.6±0.6）相比，浓度为1000μg/ml的海巴戟提取物能有效抑制白色念珠菌的生长（16.6±0.3）。发现这是一种剂量依赖性反应。
结论
海巴戟果实提取物对白色念珠菌具有抗真菌作用，且抑制作用随浓度而变化。
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