Maoulainine F-M-R, Elidrissi N-S, Chkil G, Abba F, Soraa N, Chabaa L, Amine M, Aboussad A
Unité de recherche sur l'enfance, la santé et le développement, faculté de médecine, université Cadi-Ayyad, Marrakech, Maroc; Service de réanimation néonatale, hôpital Mère-Enfant, CHU Mohammed VI, Marrakech, Maroc.
Unité de recherche sur l'enfance, la santé et le développement, faculté de médecine, université Cadi-Ayyad, Marrakech, Maroc; Service de réanimation néonatale, hôpital Mère-Enfant, CHU Mohammed VI, Marrakech, Maroc.
Arch Pediatr. 2014 Sep;21(9):938-43. doi: 10.1016/j.arcped.2014.04.033. Epub 2014 Jun 30.
In neonatal intensive care units, the incidence of nosocomial infection is high. This study aimed to determine the epidemiology of a nosocomial bacterial infection in the neonatal intensive care unit of Mohamed VI university hospital. A total of 702 newborns were included in this study. Of the 702 neonates studied, 91 had developed a nosocomial infection. The incidence rate was 13% and incidence density was 21.2 per 1000 patient-days. The types of infection were: bloodstream infections (89%), pneumonia (6.6%), meningitis (3.3%), and urinary tract infections (1.1%). Nosocomial infection was particularly frequent in cases of low birth weight, prematurity, young age at admission, umbilical venous catheter, and mechanical ventilation. Multiresistant bacteria included enterobacteria producing betalactamase (76.9%), especially enterobacteria that were dominated by Klebsiella pneumoniae (39.7%). The mortality rate was 52.7% in nosocomial infections, 19 (20.87%) of whom had septic shock. The results of this study show that nosocomial infection is an intrahospital health problem that could be remedied by a prevention strategy.
在新生儿重症监护病房，医院感染的发生率很高。本研究旨在确定穆罕默德六世大学医院新生儿重症监护病房医院细菌性感染的流行病学情况。本研究共纳入702名新生儿。在研究的702名新生儿中，91名发生了医院感染。发病率为13%，发病密度为每1000患者日21.2例。感染类型包括：血流感染（89%）、肺炎（6.6%）、脑膜炎（3.3%）和尿路感染（1.1%）。医院感染在低出生体重、早产、入院时年龄小、脐静脉导管和机械通气的病例中尤为常见。多重耐药菌包括产β-内酰胺酶的肠杆菌（76.9%），尤其是以肺炎克雷伯菌为主的肠杆菌（39.7%）。医院感染的死亡率为52.7%，其中19例（20.87%）发生感染性休克。本研究结果表明，医院感染是一个可通过预防策略加以纠正的院内健康问题。
