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口腔卫生用品、药物及毒品——牙齿侵蚀的潜在病因

Oral hygiene products, medications and drugs - hidden aetiological factors for dental erosion.

作者信息

Hellwig Elmar, Lussi Adrian

机构信息

Department of Operative Dentistry and Periodontology, Center of Dental Medicine, University of Freiburg, Freiburg, Germany.

出版信息

Monogr Oral Sci. 2014;25:155-62. doi: 10.1159/000359942. Epub 2014 Jun 26.

Abstract

Acidic or EDTA-containing oral hygiene products and acidic medicines have the potential to soften dental hard tissues. The low pH of oral care products increases the chemical stability of some fluoride compounds and favours the incorporation of fluoride ions in the lattice of hydroxyapatite and the precipitation of calcium fluoride on the tooth surface. This layer has some protective effect against an erosive attack. However, when the pH is too low or when no fluoride is present these protecting effects are replaced by direct softening of the tooth surface. Oral dryness can occur as a consequence of medication such as tranquilizers, antihistamines, antiemetics and antiparkinsonian medicaments or of salivary gland dysfunction. Above all, patients should be aware of the potential demineralization effects of oral hygiene products with low pH. Acetyl salicylic acid taken regularly in the form of multiple chewable tablets or in the form of headache powder, as well as chewing hydrochloric acids tablets for the treatment of stomach disorders, can cause erosion. There is most probably no direct association between asthmatic drugs and erosion on the population level. Consumers and health professionals should be aware of the potential of tooth damage not only by oral hygiene products and salivary substitutes but also by chewable and effervescent tablets. Several paediatric medications show a direct erosive potential in vitro. Clinical proof of the occurrence of erosion after use of these medicaments is still lacking. However, regular and prolonged use of these medicaments might bear the risk of causing erosion. Additionally, it can be assumed that patients suffering from xerostomia should be aware of the potential effects of oral hygiene products with low pH and high titratable acidity.

摘要

含酸性物质或乙二胺四乙酸(EDTA)的口腔卫生用品以及酸性药物有可能使牙齿硬组织软化。口腔护理产品的低pH值增加了某些氟化物的化学稳定性,并有利于氟离子融入羟基磷灰石晶格以及在牙齿表面沉淀氟化钙。这一层对侵蚀攻击有一定的保护作用。然而,当pH值过低或不存在氟化物时,这些保护作用就会被牙齿表面的直接软化所取代。口腔干燥可能是由于服用镇静剂、抗组胺药、止吐药和抗帕金森病药物等药物或唾液腺功能障碍所致。最重要的是,患者应该意识到低pH值口腔卫生产品的潜在脱矿作用。定期以多片咀嚼片形式或头痛粉形式服用乙酰水杨酸,以及咀嚼用于治疗胃部疾病的盐酸片,都可能导致牙齿侵蚀。在人群层面上,哮喘药物与牙齿侵蚀之间很可能没有直接关联。消费者和健康专业人员不仅应该意识到牙齿损伤不仅可能由口腔卫生产品和唾液替代品造成,还可能由咀嚼片和泡腾片造成。几种儿科药物在体外显示出直接的侵蚀潜力。使用这些药物后发生牙齿侵蚀的临床证据仍然缺乏。然而,长期定期使用这些药物可能存在导致牙齿侵蚀的风险。此外,可以推测,患有口干症的患者应该意识到低pH值和高可滴定酸度的口腔卫生产品的潜在影响。

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