Yanke Adam B, Wuerz Thomas, Saltzman Bryan M, Butty Davietta, Cole Brian J
Department of Orthopedic Surgery, Rush University Medical Center, 1611 W Harrison Street, Chicago, IL 60612, USA.
Department of Orthopedic Surgery, Rush University Medical Center, 1611 W Harrison Street, Chicago, IL 60612, USA.
Clin Sports Med. 2014 Jul;33(3):477-500. doi: 10.1016/j.csm.2014.03.004. Epub 2014 May 17.
Treatment of patellofemoral chondral defects is fraught with difficulty because of the generally inferior outcomes and significant biomechanical complexity of the joint. Noyes and Barber-Westin38 performed a systematic review of large (>4 cm2) patellofemoral ACI (11 studies), PFA (5 studies), and osteochondral allografting (2 studies) in patients younger than 50 years. Respectively, failures or poor outcomes were noted in 8% to 60% after ACI, 22% after PFA, and 53% after osteochondral allograft treatment. As noted in the outcome reviews earlier, unacceptable complication and reoperation rates were reported from all 3 procedures, and it was concluded that each operation had unpredictable results for this patient demographic. This study highlights the importance of strict indications and working to address all concomitant diseases to decrease revision rate. Outcomes are most predictable in young patients with low BMI and unipolar defects lower than 4 cm2.
髌股关节软骨损伤的治疗充满困难,这是由于总体疗效欠佳以及该关节显著的生物力学复杂性。诺伊斯和巴伯 - 韦斯汀对50岁以下患者的大面积(>4平方厘米)髌股关节自体软骨细胞移植(11项研究)、髌股关节置换(5项研究)和骨软骨异体移植(2项研究)进行了系统评价。自体软骨细胞移植后分别有8%至60%出现失败或不良结果,髌股关节置换后为22%,骨软骨异体移植治疗后为53%。如前文结果综述中所述,所有这三种手术均报告了不可接受的并发症和再次手术率,得出的结论是,对于这一患者群体,每种手术的结果都不可预测。这项研究强调了严格掌握适应症以及努力处理所有并存疾病以降低翻修率的重要性。在体重指数较低且单极缺损面积小于4平方厘米的年轻患者中,结果最具可预测性。