Zhou Yang, Chen Mu-Nan, Liu Yang
Department of Radiology, Harbin Medical University Cancer Hospital Harbin 150081, Heilongjiang Province, China.
Department of PET-CT/MR, Harbin Medical University Cancer Hospital Harbin 150081, Heilongjiang Province, China.
Int J Clin Exp Med. 2014 May 15;7(5):1331-5. eCollection 2014.
The present study was aimed to study feasibility of low-dose contrast agent in cerebral CT angiography (CTA) to alleviate some side effects and costs associated with routine doses of contrast agent. Sixty patients suspected to have cerebral artery disease were randomly selected to receive either low-dose (60 mL) contrast agent or routine-dose (100 mL) contrast agent. CTA included transverse images, volume rendering (VR), and maximum intensity projection (MIP) images. Developing strength, image noise, and structure display effects of the cerebral artery were compared between groups. The developing strength and image noise of the cerebral artery were equivalent between groups (P > 0.05). No statistical differences were observed in structure display effects of the cerebral artery or in radiological diagnosis between groups (P > 0.05). Application of the low-dose contrast agent is feasible and offers comparable diagnostic capabilities in cerebral CT angiography.
本研究旨在探讨低剂量造影剂在脑CT血管造影（CTA）中的可行性，以减轻与常规剂量造影剂相关的一些副作用和成本。随机选择60例疑似患有脑动脉疾病的患者，分别接受低剂量（60 mL）造影剂或常规剂量（100 mL）造影剂。CTA包括横断图像、容积再现（VR）和最大密度投影（MIP）图像。比较两组脑动脉的显影强度、图像噪声和结构显示效果。两组脑动脉的显影强度和图像噪声相当（P>0.05）。两组在脑动脉结构显示效果或放射学诊断方面均未观察到统计学差异（P>0.05）。低剂量造影剂在脑CT血管造影中的应用是可行的，并且具有相当的诊断能力。
