免疫功能低下老年患者的诺卡菌性脑脓肿：一例报告并文献复习
Nocardial brain abscess in an immunocompromised old patient: a case report and review of literature.
作者信息
Tang Hailiang, Mao Tianming, Gong Ye, Mao Ying, Xie Qing, Wang Daijun, Zhu Hongda, Chen Xiancheng, Zhou Liangfu
机构信息
Department of Neurosurgery, Huashan Hospital Shanghai 200040, China.
Department of Neurosurgery, Taizhou Municipal Hospital Zhejiang Province 318000, China.
出版信息
Int J Clin Exp Med. 2014 May 15;7(5):1480-2. eCollection 2014.
BACKGROUND
Nocardial brain abscess is a rare central nervous system (CNS) infection with high morbidity and mortality. The infection is acquired through inhalation or direct contact with the bacteria, and could spreads through blood transmission. Nocardial brain abscess is usually associated with immunocompromised patients, but sometimes may appear in healthy individuals. Treatment is based on stereotaxic aspiration or surgical resection, and antibiotics therapy for several months.
CLINICAL PRESENTATION
We presented one case of nocardial brain abscess treated at our department with review the literature. The patient was 65-year-old with ANCA polyangitis. She had oral methylprednisolone tablets treatment for over 6 months. The patient was treated with surgical evacuation and long-term antibiotics. The patient recovered well at discharge.
CONCLUSION
Nocardial brain abscess is a rare CNS infection that needs to be differentiated from other brain lesions. It could occur in immunocompromised patients or healthy individuals. Treatment includes surgical intervention and long-term antibiotics therapy.
背景
诺卡菌性脑脓肿是一种罕见的中枢神经系统（CNS）感染，发病率和死亡率都很高。该感染通过吸入或直接接触细菌获得，并可通过血液传播扩散。诺卡菌性脑脓肿通常与免疫功能低下的患者有关，但有时也可能出现在健康个体中。治疗基于立体定向抽吸或手术切除，并进行数月的抗生素治疗。
临床表现
我们报告了在我科治疗的一例诺卡菌性脑脓肿病例并复习了文献。该患者为65岁患有抗中性粒细胞胞浆抗体（ANCA）相关性血管炎。她接受口服甲泼尼龙片治疗超过6个月。该患者接受了手术引流和长期抗生素治疗。患者出院时恢复良好。
结论
诺卡菌性脑脓肿是一种罕见的中枢神经系统感染，需要与其他脑部病变相鉴别。它可发生于免疫功能低下患者或健康个体。治疗包括手术干预和长期抗生素治疗。
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