Iranpour Dariush, Pourbehi Mohammadreza, Afroozandeh Marzieh, Davoodi Nafiseh, Bidel-Khoshbakht Sara, Nabipour Iraj, Javadi Hamid, Seyedabadi Mohammad, Assadi Majid
The Persian Gulf Nuclear Medicine, Research Center, Bushehr University of Medical Sciences, Bushehr 3631, Iran.
Hell J Nucl Med. 2014 May-Aug;17(2):111-5. doi: 10.1967/s002449910138. Epub 2014 Jul 5.
Based on data, there may exist an association between low bone mineral density (BMD) and atherosclerosis. This study aimed to investigate the association between BMD and coronary artery disease (CAD). In this study the possible association of BMD with CAD in 65 men with CAD and in 49 men with normal angiography as well as in 51 women with CAD and in 51 normal women was investigated. Both spinal and femoral BMD values for men were higher than those of women (P<0.05). Neither femoral nor spinal BMD values were different in patients with or without CAD. In addition, BMD values were not associated with the severity of CAD. Body mass index (BMI) was positively correlated with BMD both in men and women, whereas age and anti-diabetic treatment were linked with lower BMD in women. In conclusion, in this study CAD was not related to low BMD. However, BMI was an independent predictor of diminished BMD.
基于数据，低骨矿物质密度（BMD）与动脉粥样硬化之间可能存在关联。本研究旨在调查BMD与冠状动脉疾病（CAD）之间的关联。在本研究中，对65例CAD男性患者、49例血管造影正常的男性、51例CAD女性患者和51例正常女性中BMD与CAD的可能关联进行了调查。男性的脊柱和股骨BMD值均高于女性（P<0.05）。CAD患者和非CAD患者的股骨和脊柱BMD值均无差异。此外，BMD值与CAD的严重程度无关。体重指数（BMI）在男性和女性中均与BMD呈正相关，而年龄和抗糖尿病治疗与女性较低的BMD有关。总之，在本研究中，CAD与低BMD无关。然而，BMI是BMD降低的独立预测因素。
