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射频双极止血密封器可减少接受多节段脊柱融合手术患者的失血量、输血需求及费用:一项病例对照研究。

Radiofrequency bipolar hemostatic sealer reduces blood loss, transfusion requirements, and cost for patients undergoing multilevel spinal fusion surgery: a case control study.

作者信息

Frank Steven M, Wasey Jack O, Dwyer Ian M, Gokaslan Ziya L, Ness Paul M, Kebaish Khaled M

机构信息

Department of Anesthesiology/Critical Care Medicine, The Johns Hopkins Medical Institutions, Zayed 6208, 1800 Orleans Street, Baltimore 21287, MD, USA.

出版信息

J Orthop Surg Res. 2014 Jul 5;9:50. doi: 10.1186/s13018-014-0050-2.

Abstract

BACKGROUND

A relatively new method of electrocautery, the radiofrequency bipolar hemostatic sealer (RBHS), uses saline-cooled delivery of energy, which seals blood vessels rather than burning them. We assessed the benefits of RBHS as a blood conservation strategy in adult patients undergoing multilevel spinal fusion surgery.

METHODS

In a retrospective cohort study, we compared blood utilization in 36 patients undergoing multilevel spinal fusion surgery with RBHS (Aquamantys, Medtronic, Minneapolis, MN, USA) to that of a historical control group (n = 38) matched for variables related to blood loss. Transfusion-related costs were calculated by two methods.

RESULTS

Patient characteristics in the two groups were similar. Intraoperatively, blood loss was 55% less in the RBHS group than in the control group (810 ± 530 vs. 1,800 ± 1,600 mL; p = 0.002), and over the entire hospital stay, red cell utilization was 51% less (2.4 ± 3.4 vs. 4.9 ± 4.5 units/patient; p = 0.01) and plasma use was 56% less (1.1 ± 2.4 vs. 2.5 ± 3.4 units/patient; p = 0.03) in the RBHS group. Platelet use was 0.1 ± 0.5 and 0.3 ± 0.6 units/patient in the RBHS and control groups, respectively (p = 0.07). The perioperative decrease in hemoglobin was less in the RBHS group than in the control group (-2.0 ± 2.2 vs. -3.2 ± 2.1 g/dL; p = 0.04), and hemoglobin at discharge was higher in the RBHS group (10.5 ± 1.4 vs. 9.7 ± 0.9 g/dL; p = 0.01). The estimated transfusion-related cost savings were $745/case by acquisition cost and approximately 3- to 5-fold this amount by activity-based cost.

CONCLUSIONS

The use of RBHS in patients undergoing multilevel spine fusion surgery can conserve blood, promote higher hemoglobin levels, and reduce transfusion-related costs.

摘要

背景

一种相对较新的电灼方法,即射频双极止血密封器(RBHS),采用盐水冷却能量传输方式,它能封闭血管而非灼烧血管。我们评估了RBHS作为一种血液保护策略在接受多节段脊柱融合手术的成年患者中的益处。

方法

在一项回顾性队列研究中,我们将36例使用RBHS(美国明尼阿波利斯美敦力公司的Aquamantys)进行多节段脊柱融合手术的患者的血液使用情况与一个按失血相关变量匹配的历史对照组(n = 38)进行了比较。通过两种方法计算输血相关成本。

结果

两组患者的特征相似。术中,RBHS组的失血量比对照组少55%(810±530 vs. 1,800±1,600 mL;p = 0.002),在整个住院期间,RBHS组的红细胞使用量少51%(2.4±3.4 vs. 4.9±4.5单位/患者;p = 0.01),血浆使用量少56%(1.1±2.4 vs. 2.5±3.4单位/患者;p = 0.03)。RBHS组和对照组的血小板使用量分别为0.1±0.5和0.3±0.6单位/患者(p = 0.07)。RBHS组围手术期血红蛋白的下降幅度小于对照组(-2.0±2.2 vs. -3.2±2.1 g/dL;p = 0.04),出院时RBHS组的血红蛋白水平更高(10.5±1.4 vs. 9.7±0.9 g/dL;p = 0.01)。按购置成本估算,每例患者输血相关成本节约745美元,按作业成本法估算约为此金额的3至5倍。

结论

在接受多节段脊柱融合手术的患者中使用RBHS可节约血液、提高血红蛋白水平并降低输血相关成本。

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