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1
Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork.
Nat Struct Mol Biol. 2014 Aug;21(8):664-70. doi: 10.1038/nsmb.2851. Epub 2014 Jul 6.
2
Quality control mechanisms exclude incorrect polymerases from the eukaryotic replication fork.
Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):675-680. doi: 10.1073/pnas.1619748114. Epub 2017 Jan 9.
3
CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication.
Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15390-5. doi: 10.1073/pnas.1418334111. Epub 2014 Oct 13.
5
Reconstitution of translesion synthesis reveals a mechanism of eukaryotic DNA replication restart.
Nat Struct Mol Biol. 2020 May;27(5):450-460. doi: 10.1038/s41594-020-0418-4. Epub 2020 Apr 27.
6
Fidelity consequences of the impaired interaction between DNA polymerase epsilon and the GINS complex.
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7
Impairment of the non-catalytic subunit Dpb2 of DNA Pol ɛ results in increased involvement of Pol δ on the leading strand.
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8
Strand-specific analysis shows protein binding at replication forks and PCNA unloading from lagging strands when forks stall.
Mol Cell. 2014 Nov 20;56(4):551-63. doi: 10.1016/j.molcel.2014.09.017. Epub 2014 Oct 23.
9
The Eukaryotic CMG Helicase at the Replication Fork: Emerging Architecture Reveals an Unexpected Mechanism.
Bioessays. 2018 Mar;40(3). doi: 10.1002/bies.201700208. Epub 2018 Feb 6.
10
Increased contribution of DNA polymerase delta to the leading strand replication in yeast with an impaired CMG helicase complex.
DNA Repair (Amst). 2022 Feb;110:103272. doi: 10.1016/j.dnarep.2022.103272. Epub 2022 Jan 6.

引用本文的文献

1
DNA polymerase α-primase can function as a translesion DNA polymerase.
bioRxiv. 2025 Jul 2:2025.07.02.662785. doi: 10.1101/2025.07.02.662785.
3
4
Competition for the nascent leading strand shapes the requirements for PCNA loading in the replisome.
EMBO J. 2025 Apr;44(8):2298-2322. doi: 10.1038/s44318-025-00386-4. Epub 2025 Feb 28.
6
A tale of two strands: Decoding chromatin replication through strand-specific sequencing.
Mol Cell. 2025 Jan 16;85(2):238-261. doi: 10.1016/j.molcel.2024.10.035.
7
DNA polymerase ζ is a robust reverse transcriptase.
bioRxiv. 2024 Sep 28:2024.09.27.615452. doi: 10.1101/2024.09.27.615452.
8
Revised mechanism of hydroxyurea-induced cell cycle arrest and an improved alternative.
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9
Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol ε.
Nat Struct Mol Biol. 2024 Dec;31(12):1921-1931. doi: 10.1038/s41594-024-01370-y. Epub 2024 Aug 7.
10
Mechanism of PCNA loading by Ctf18-RFC for leading-strand DNA synthesis.
Science. 2024 Aug 2;385(6708):eadk5901. doi: 10.1126/science.adk5901.

本文引用的文献

1
Domain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progression.
Proc Natl Acad Sci U S A. 2014 May 6;111(18):E1899-908. doi: 10.1073/pnas.1404063111. Epub 2014 Apr 16.
2
Prereplicative complexes assembled in vitro support origin-dependent and independent DNA replication.
EMBO J. 2014 Mar 18;33(6):605-20. doi: 10.1002/embj.201387369. Epub 2014 Feb 24.
3
Origin plasticity during budding yeast DNA replication in vitro.
EMBO J. 2014 Mar 18;33(6):621-36. doi: 10.1002/embj.201387278. Epub 2014 Feb 24.
4
Helicase activation and establishment of replication forks at chromosomal origins of replication.
Cold Spring Harb Perspect Biol. 2013 Dec 1;5(12):a010371. doi: 10.1101/cshperspect.a010371.
5
Principles and concepts of DNA replication in bacteria, archaea, and eukarya.
Cold Spring Harb Perspect Biol. 2013 Jul 1;5(7):a010108. doi: 10.1101/cshperspect.a010108.
6
Helicase loading at chromosomal origins of replication.
Cold Spring Harb Perspect Biol. 2013 Jun 1;5(6):a010124. doi: 10.1101/cshperspect.a010124.
7
Replication clamps and clamp loaders.
Cold Spring Harb Perspect Biol. 2013 Apr 1;5(4):a010165. doi: 10.1101/cshperspect.a010165.
8
Dpb2 integrates the leading-strand DNA polymerase into the eukaryotic replisome.
Curr Biol. 2013 Apr 8;23(7):543-52. doi: 10.1016/j.cub.2013.02.011. Epub 2013 Mar 14.
9
Structure and evolutionary origins of the CMG complex.
Chromosoma. 2013 Mar;122(1-2):47-53. doi: 10.1007/s00412-013-0397-x. Epub 2013 Feb 15.
10
Okazaki fragment metabolism.
Cold Spring Harb Perspect Biol. 2013 Feb 1;5(2):a010173. doi: 10.1101/cshperspect.a010173.

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