Storey Philip, Alshareef Rayan, Khuthaila Mohammed, London Nikolas, Leiby Benjamin, DeCroos Char, Kaiser Richard
*Mid Atlantic Retina, Wills Eye Hospital, Philadelphia, Pennsylvania; and †Division of Biostatistics, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania.
Retina. 2014 Oct;34(10):1945-51. doi: 10.1097/IAE.0000000000000216.
To compare using pars plana vitrectomy (PPV) combined with a scleral buckle versus primary vitrectomy alone in patients with rhegmatogenous retinal detachment at high risk for postoperative proliferative vitreoretinopathy (PVR).
Six hundred and seventy-eight patients were identified from billing data as having rhegmatogenous retinal detachment between April 1, 2010 and August 1, 2012. Patients were considered at high risk for PVR if they presented with retinal detachment in 2 or more quadrants, retinal tears >1 clock hour, preoperative PVR, or vitreous hemorrhage.
Of the 678 patients with rhegmatogenous retinal detachment, 65 were identified as high risk for PVR. Thirty-six patients were treated with simultaneous PPV-scleral buckle and 29 patients were treated with PPV alone, with an overall success rate of 63.1%. The use of PPV-scleral buckle was associated with significantly higher single surgery anatomical success compared with patients treated with PPV alone (odds ratio, 3.24; 95% confidence interval, 1.12-9.17; P = 0.029). Visual acuity at 3 months postprocedure or final follow-up was no different between the treatment groups. Overall, 23.1% of patients developed postoperative PVR with no difference between surgical approaches.
For patients at high risk for PVR, PPV-scleral buckle was associated with significantly higher rates of anatomical success compared with PPV alone.
比较在术后发生增殖性玻璃体视网膜病变(PVR)风险较高的孔源性视网膜脱离患者中,使用玻璃体切除术(PPV)联合巩膜扣带术与单纯一期玻璃体切除术的效果。
从计费数据中识别出2010年4月1日至2012年8月1日期间患有孔源性视网膜脱离的678例患者。如果患者出现2个或更多象限的视网膜脱离、视网膜裂孔大于1个钟点、术前PVR或玻璃体出血,则被认为是PVR高风险患者。
在678例孔源性视网膜脱离患者中,65例被确定为PVR高风险患者。36例患者接受了PPV联合巩膜扣带术,29例患者仅接受了PPV治疗,总体成功率为63.1%。与仅接受PPV治疗的患者相比,使用PPV联合巩膜扣带术的单次手术解剖成功率显著更高(优势比,3.24;95%置信区间,1.12 - 9.17;P = 0.029)。治疗组术后3个月或最终随访时的视力无差异。总体而言,23.1%的患者发生了术后PVR,手术方式之间无差异。
对于PVR高风险患者,与单纯PPV相比,PPV联合巩膜扣带术的解剖成功率显著更高。