Rajsirisongsri Pongthep, Patikulsila Direk, Phinyo Phichayut, Kunavisarut Paradee, Chaikitmongkol Voraporn, Nanegrungsunk Onnisa, Apivatthakakul Atitaya, Seetasut Sutheerada, Tantivit Yaowaret, Krisanuruks Napatsorn, Sangkaew Apisara, Watanachai Nawat, Choovuthayakorn Janejit
Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Clinical Epidemiology and Clinical Statistics Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Clin Ophthalmol. 2024 Dec 23;18:3913-3923. doi: 10.2147/OPTH.S494849. eCollection 2024.
To evaluate the anatomical and visual outcomes of patients with rhegmatogenous retinal detachment (RRD) who received primary repair by combined pars plana vitrectomy with scleral buckling (PPV/SB) or pars plana vitrectomy (PPV) alone by using a propensity analysis.
This study was a single center retrospective observational study. Medical records of patients who underwent surgical interventions between January 2013 and December 2019 were retrospectively reviewed. The single surgery anatomic success (SSAS) and final anatomic success were the primary outcomes, whereas the final visual acuity changes was the secondary outcome.
This study included a total of 683 patients (683 eyes), with a median (interquartile range, IQR) follow-up duration of 13 (5.5 to 28.8) months. Of them, 211 patients (30.9%) underwent PPV/SB, while 472 patients (69.1%) underwent PPV as their primary procedure. The two treatment groups did not significantly differ in the risk of achieving SSAS (weighted risk difference: 0.012, 95% confidence interval (CI): -0.067 to 0.092, p value = 0.776) or achieving final retinal anatomic attachment (weighted risk difference: -0.038, 95% CI: -0.106 to 0.030, p value = 0.272). The occurrence of proliferative vitreoretinopathy was identical between the two treatment groups (56 patients (26.5%) for the PPV/SB group and 104 patients (22.0%) for the PPV group), p = 0.199. Nonetheless, the patients who received PPV alone showed a significantly greater mean improvement in VA (weighted mean difference; 0.295, 95% CI; 0.150, 0.440, p <0.001).
This work supports the findings that adding SB to PPV had little impact on anatomical results (either a single surgical success rate or the overall final success rate) for RRD repair. Although PPV alone is shown to improve vision, confirmation of these associations requires further prospective studies using standardized surgical techniques.
通过倾向分析评估接受单纯玻璃体切除联合巩膜扣带术(PPV/SB)或单纯玻璃体切除术(PPV)进行原发性修复的孔源性视网膜脱离(RRD)患者的解剖学和视觉效果。
本研究为单中心回顾性观察研究。回顾性分析2013年1月至2019年12月期间接受手术干预患者的病历。单次手术解剖成功(SSAS)和最终解剖成功为主要结局,而最终视力变化为次要结局。
本研究共纳入683例患者(683只眼),中位(四分位间距,IQR)随访时间为13(5.5至28.8)个月。其中,211例患者(30.9%)接受了PPV/SB,472例患者(69.1%)接受了PPV作为主要手术。两组在实现SSAS的风险(加权风险差异:0.012,95%置信区间(CI):-0.067至0.092,p值 = 0.776)或实现最终视网膜解剖复位方面(加权风险差异:-0.038,95% CI:-0.106至0.030,p值 = 0.272)无显著差异。两组增生性玻璃体视网膜病变的发生率相同(PPV/SB组56例患者(26.5%),PPV组104例患者(22.0%)),p = 0.199。然而,单纯接受PPV的患者视力平均改善明显更大(加权平均差异;0.295,95% CI;0.150,0.440,p <0.001)。
本研究支持以下发现,即PPV联合SB对RRD修复的解剖学结果(单次手术成功率或总体最终成功率)影响不大。虽然单纯PPV显示可改善视力,但要证实这些关联需要使用标准化手术技术进行进一步的前瞻性研究。