Liu Wei, Yu Xin, Li Yahui, Kuang Chunxiang
Department of Chemistry, Tongji University, Siping Road 1239, Shanghai 200092, China.
Chem Commun (Camb). 2014 Aug 25;50(66):9291-4. doi: 10.1039/c4cc04129a.
Using Ag2CO3 as an additive, we developed the Pd-catalyzed intermolecular C-H/C-H cross-coupling of pyridine N-oxides with five-membered heterocycles such as 1-benzyl-1,2,3-triazoles, thiophens and furans. This protocol provides an efficient and regioselective approach for the synthesis of unsymmetrical biheteroaryl molecules.
我们以碳酸银为添加剂，开发了钯催化的吡啶氮氧化物与五元杂环（如1-苄基-1,2,3-三唑、噻吩和呋喃）之间的分子间C-H/C-H交叉偶联反应。该方法为合成不对称双杂芳基分子提供了一种高效且区域选择性的途径。
