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[α/β干扰素和γ干扰素制剂对实验性葡萄球菌感染中巨噬细胞功能活性的影响]

[The effect of alpha/beta and gamma interferon preparations on the functional activity of macrophages in experimental staphylococcal infections].

作者信息

Vikhot' N E, Spivak N Ia, Chernaia L N, Paster E U

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1989 Apr(4):57-60.

PMID:2500002
Abstract

The preparations of alpha/beta- and gamma-interferons have been shown to stimulate the functional activity characteristics of mouse macrophages (phagocytosis, spreading, contacts with lymphocytes, bactericidal properties) obtained from the peritoneal exudate of intact animals and those infected with staphylococci. The immunomodulating action of gamma-interferon is more pronounced than that of the preparation of alpha/beta-interferon.

摘要

已证明,α/β干扰素和γ干扰素制剂能刺激从小鼠腹腔渗出液中获得的巨噬细胞的功能活性特征(吞噬作用、铺展、与淋巴细胞的接触、杀菌特性),这些巨噬细胞来自未受损伤的动物以及感染葡萄球菌的动物。γ干扰素的免疫调节作用比α/β干扰素制剂更为显著。

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