Vasilenko R N, Denisov L A, Galaktionov V G
Zh Mikrobiol Epidemiol Immunobiol. 1989 Jul(7):100-4.
The influence of human recombinant alpha 2-interferon (reaferon) on the parameters of the phagocytic activity of mouse peritoneal macrophages (migration, spreading, adhesion and absorption of corpuscular antigen) has been studied. Reaferon in doses of 5-5 X 10(2) I. U./ml has been found to produce a stimulating effect on all parameters under study. The data obtained in this study suggest that a stimulating effect on the functional activity of macrophages is the same for recombinant (alpha 2) interferon and natural alpha-interferon.
研究了人重组α2干扰素(利扰素)对小鼠腹腔巨噬细胞吞噬活性参数(迁移、铺展、黏附及颗粒性抗原吸收)的影响。已发现剂量为5 - 5×10²国际单位/毫升的利扰素对所研究的所有参数均产生刺激作用。本研究获得的数据表明,重组(α2)干扰素和天然α干扰素对巨噬细胞功能活性的刺激作用相同。