Kjeldsberg E, Rollag H, Lund H, Holberg-Pettersen M, Degré M
Acta Pathol Microbiol Immunol Scand B. 1985 Jun;93(3):165-70. doi: 10.1111/j.1699-0463.1985.tb02871.x.
The influence of a homologous gamma interferon preparation (MuIFN-gamma) on in vitro spreading of freshly-seeded unelicited mouse peritoneal macrophages (MPM) was tested. Light microscopy and scanning electron microscopy observations gave comparable results. Addition of MuIFN-gamma enhanced the spreading on solid surfaces, especially 3-5 hours after seeding. Maximal effect was achieved with 10 units of IFN. Addition of specific anti-MuIFN-gamma or treatment of the preparation at pH 2 eliminated both antiviral activity and effect on spreading of MPM.
测试了同源γ干扰素制剂（MuIFN-γ）对新接种的未致敏小鼠腹腔巨噬细胞（MPM）体外铺展的影响。光学显微镜和扫描电子显微镜观察结果相当。添加MuIFN-γ可增强在固体表面的铺展，尤其是接种后3至5小时。10单位的干扰素可达到最大效果。添加特异性抗MuIFN-γ或在pH 2条件下处理该制剂可消除抗病毒活性以及对MPM铺展的影响。
