Reichl Kyle D, Radosevich Alexander T
Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA.
Chem Commun (Camb). 2014 Aug 25;50(66):9302-5. doi: 10.1039/c4cc03415e.
Z-Enediynes are prepared by a vicinal dialkynylation of triaryl(arylethynyl)phosphonium cations. The method, which proceeds under mild transition metal-free conditions, can be conducted on multigram scale as a one-pot, phosphine-mediated synthetic cycle giving enediyne products with excellent control of configuration.
Z-烯二炔是通过三芳基（芳基乙炔基）鏻阳离子的邻位二炔基化反应制备的。该方法在温和的无过渡金属条件下进行，可以以多克规模进行一锅法反应，通过膦介导的合成循环，以优异的构型控制得到烯二炔产物。
