Antoine Sunya-Lee, Pieper Dawid, Mathes Tim, Eikermann Michaela
Institute for Research in Operative Medicine, Faculty of Health - School of Medicine, Witten/Herdecke University, Ostmerheimer Str, 200, Building 38, D- 51109 Cologne, Germany.
BMC Endocr Disord. 2014 Jul 7;14:53. doi: 10.1186/1472-6823-14-53.
Oral medication for patients with type 2 diabetes mellitus plays an important role in diabetes care and is associated with a high level self-care behavior and self-management. However, poor adherence to diabetes treatment is common which causes severe health complications and increased mortality. Barriers to adherence may consist of complex treatment regimens often along with long-term multi-therapies, side effects due to the medication as well as insufficient, incomprehensible or confusing information or instructions provided by the health care provider. Multidisciplinary approaches can support adherence success and can enable a more effective management of diabetes care. One approach in diabetes care can be the involvement of a pharmacist. The aim was to analyze the effectiveness of adherence-enhancing pharmacist interventions for oral medication in type 2 diabetes mellitus.
A systematic review of randomized controlled trials. The study quality was assessed with the Cochrane risk of bias tool.
Of 491 hits, six publications were included. Two studies mainly examining educational interventions showed a significant improvement in adherence. Moreover, the quality of the included studies was deficient.
Although pharmacist interventions might potentially improve adherence to type 2 diabetes mellitus medication, high-quality studies are needed to assess effectiveness.
2型糖尿病患者的口服药物治疗在糖尿病护理中起着重要作用，并且与高水平的自我护理行为和自我管理相关。然而，糖尿病治疗依从性差很常见，这会导致严重的健康并发症并增加死亡率。依从性障碍可能包括通常伴随着长期多种治疗方法的复杂治疗方案、药物的副作用以及医疗保健提供者提供的信息或指导不足、难以理解或令人困惑。多学科方法可以支持依从性的成功，并能更有效地管理糖尿病护理。糖尿病护理中的一种方法可以是药剂师的参与。目的是分析增强2型糖尿病患者口服药物依从性的药剂师干预措施的有效性。
对随机对照试验进行系统评价。使用Cochrane偏倚风险工具评估研究质量。
在491条检索结果中，纳入了6篇出版物。两项主要研究教育干预措施的研究显示依从性有显著改善。此外，纳入研究的质量不足。
虽然药剂师干预可能会潜在地提高2型糖尿病药物治疗的依从性，但需要高质量的研究来评估其有效性。
