Keyhanian Sh, Ebrahimifard M, Zandi M
Associate Professor of Oncologist, Islamic Azad University of Tonekabon, Tonekabon, Iran.
Young Researchers and Elite Club, Tonekabon Branch, Islamic Azad University, Tonekabon, Iran.
Iran J Ped Hematol Oncol. 2014;4(2):72-7. Epub 2014 Apr 20.
Blood is a liquid tissue in which dissolved with abundant chemical factors and millions of different cells The reduction of unwanted side effects, especially diseases that emerge through blood such as HIV and hepatitis, has a significant role for modern medicine of transfusion and transplantation. The issues and costs of human blood collection and storage, direct this procedure towards the use of alternatives blood. Two important research fields of this area were oxygen carriers based on hemoglobin and perfluoro chemicals. While they do not have the same quality as the blood cell products, the oxygen carrier solutions have potential clinical and non-clinical applications. The result showed that these products can reach to the body tissues easier than normal red blood cells, and can control the oxygen directly. The final aim of transfusion is to establish a transfusion system with no side effects, and the fact that oxygen carrier artificial blood has this property. The article attempts to step towards solving some problems of blood transfusion through describing the properties of artificial blood alternatives.
血液是一种液体组织，其中溶解有丰富的化学因子和数百万种不同的细胞。减少不必要的副作用，尤其是通过血液传播的疾病，如艾滋病毒和肝炎，对现代输血和移植医学具有重要意义。人类血液采集和储存的问题及成本，促使这一过程朝着使用替代血液的方向发展。该领域的两个重要研究方向是基于血红蛋白的氧载体和全氟化合物。虽然氧载体溶液的质量不如血细胞产品，但它们具有潜在的临床和非临床应用。结果表明，这些产品比正常红细胞更容易到达身体组织，并且可以直接控制氧气。输血的最终目标是建立一个无副作用的输血系统，而氧载体人工血液具有这一特性。本文试图通过描述人工血液替代品的特性，朝着解决输血中的一些问题迈出一步。
