Sehgal Shelly, Goyal Prashant, Ghosh Soumyesh, Mittal Deepti, Kumar Awanindra, Singh Sompal
Department of Pathology, Swami Dayanand Hospital , Delhi, India.
Rare Tumors. 2014 May 13;6(2):5343. doi: 10.4081/rt.2014.5343.
Clear cell hidradenoma (CCH) is an uncommon skin adnexal tumor arising from eccrine glands. Although several kind of skin adnexal tumors arise in the breast tissue, CCH of the breast is an extremely rare entity. Failure to identify its cytomorphologic features and rarity of this tumor may lead to misdiagnosis on fine needle aspiration cytology. Hereby we report a case of 30-year-old female who presented with painless lump in left breast since 10 months. Fine needle aspiration cytology of lump yielded fluid material. On May-Grunwald-Giemsa stained smears, a possibility of atypical breast lesion was considered and patient was advised a biopsy examination. Final diagnosis of CCH was made on histopathologic examination. Awareness of cytomorphologic features of breast CCH will prevent misdiagnosis as malignant or atypical breast lesions and will allow for correct management of the patients.
透明细胞汗腺瘤（CCH）是一种罕见的起源于小汗腺的皮肤附属器肿瘤。虽然几种皮肤附属器肿瘤可发生于乳腺组织，但乳腺透明细胞汗腺瘤是一种极其罕见的实体。未能识别其细胞形态学特征以及该肿瘤的罕见性可能导致细针穿刺细胞学检查误诊。在此，我们报告一例30岁女性，自10个月前起左侧乳房出现无痛性肿块。肿块的细针穿刺细胞学检查获取了液体物质。在May-Grunwald-Giemsa染色涂片上，考虑为非典型乳腺病变的可能性，建议患者进行活检检查。经组织病理学检查最终诊断为透明细胞汗腺瘤。了解乳腺透明细胞汗腺瘤的细胞形态学特征将防止误诊为恶性或非典型乳腺病变，并有助于对患者进行正确的管理。
