Shalini Bahadur, Akshi Katyal, Namrata Nargotra, Shilpi Soni, Manupriya Nain
Department of Pathology, North Delhi Municipal Corporation Medical College and Hindu Rao Hospital, New Delhi, India.
Diagn Cytopathol. 2018 Jan;46(1):59-62. doi: 10.1002/dc.23791. Epub 2017 Aug 3.
Limited literature is available on the use of fine needle aspiration (FNA) for skin tumors. Awareness of cytological features of these lesions is important to prevent misdiagnosis. A 45-year-old male, presented with slowly growing swelling over the thigh since 4 years. FNA from multiple sites yielded highly cellular smears with a dual cell population consisting of cells with small round nucleus scanty cytoplasm and polygonal cells with moderate to abundant cytoplasm. Extracellular basement membrane like material was also noted. A diagnosis of benign adnexal neoplasm, suggestive of nodular hidradenoma was made. Paraffin sections showed an encapsulated dermal tumor composed of ductal and myoepithelial cells in ducts, sheets, strands with chondromyxoid stroma. A final diagnosis of chondroid syringoma was given following evaluation of histopathology slides and Immunohistochemistry. FNA interpretation of skin tumors can be challenging since literature is limited. The placement of tumors into benign or malignant category is realistic and can direct management guidelines. Greater awareness of these lesions and following stringent diagnostic criteria can help in establishing a more accurate diagnosis.
关于细针穿刺抽吸（FNA）用于皮肤肿瘤的文献有限。了解这些病变的细胞学特征对于防止误诊很重要。一名45岁男性，4年来大腿部出现缓慢生长的肿物。从多个部位进行FNA，得到细胞丰富的涂片，有双细胞群，包括核小而圆、胞质稀少的细胞和胞质中度至丰富的多边形细胞。还发现了细胞外基底膜样物质。诊断为良性附属器肿瘤，提示结节性汗腺瘤。石蜡切片显示一个包膜性真皮肿瘤，由导管内的导管细胞和肌上皮细胞、片状、条索状结构以及软骨黏液样间质组成。在对组织病理学切片和免疫组织化学进行评估后，最终诊断为软骨样汗腺螺旋瘤。由于文献有限，FNA对皮肤肿瘤的解读可能具有挑战性。将肿瘤分类为良性或恶性是现实可行的，并且可以指导管理指南。对这些病变有更高的认识并遵循严格的诊断标准有助于建立更准确的诊断。
