焦虑障碍与胰岛素依赖型 2 型糖尿病患者的生活质量受损有关：一项病例对照研究。
Anxiety disorders are associated with quality of life impairment in patients with insulin-dependent type 2 diabetes: a case-control study.
机构信息
Laboratory of Neurosciences, Graduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense (UNESC), Criciúma, SC, Brazil.
Department of Nursing, UNESC, Criciúma, SC, Brazil.
出版信息
Braz J Psychiatry. 2014 Oct-Dec;36(4):298-304. doi: 10.1590/1516-4446-2013-1230. Epub 2014 Jun 24.
OBJECTIVE
To assess the presence of anxiety disorders and quality of life in patients with insulin-dependent type 2 diabetes.
METHODS
Case-control study of 996 patients with type 2 diabetes and 2,145 individuals without diabetes. The sole inclusion criterion for the case group was insulin-dependent type 2 diabetes. We compared the case and control groups for sociodemographic variables, laboratory and clinical data, and presence of anxiety disorders. Quality of life was evaluated using the WHOQOL-BREF instrument, and the prevalence of anxiety disorder was evaluated by the Mini International Neuropsychiatric Interview (MINI).
RESULTS
Patients with diabetes had a higher prevalence of generalized anxiety disorder, panic disorder, and obsessive-compulsive disorder. The presence of these disorders in combination with type 2 diabetes was associated with worse quality of life in the physical, social, psychological, and environmental domains.
CONCLUSIONS
This study demonstrates the importance of diagnosing and treating anxiety disorders in patients with diabetes, so as to prevent more serious complications associated with these comorbidities.
目的
评估胰岛素依赖型 2 型糖尿病患者的焦虑障碍和生活质量。
方法
对 996 例 2 型糖尿病患者和 2145 例无糖尿病个体进行病例对照研究。病例组的唯一纳入标准是胰岛素依赖型 2 型糖尿病。我们比较了病例组和对照组的社会人口统计学变量、实验室和临床数据以及焦虑障碍的存在情况。使用世界卫生组织生活质量简表（WHOQOL-BREF）评估生活质量，使用迷你国际神经精神访谈（MINI）评估焦虑障碍的患病率。
结果
糖尿病患者广泛性焦虑障碍、惊恐障碍和强迫症的患病率更高。这些疾病与 2 型糖尿病并存与身体、社会、心理和环境领域的生活质量更差相关。
结论
本研究表明诊断和治疗糖尿病患者的焦虑障碍的重要性，以预防与这些合并症相关的更严重的并发症。
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