Efird Jimmy T, O'Neal Wesley T, Davies Stephen W, O'Neal Jason B, Kypson Alan P
Department of Cardiovascular Sciences, East Carolina Heart Institute, Brody School of Medicine, East Carolina University , Greenville, NC , USA .
Chronobiol Int. 2014 Nov;31(9):954-8. doi: 10.3109/07420528.2014.933842. Epub 2014 Jul 8.
The objective of this study was to test the hypothesis that there is seasonal variation in the incidence of Stanford type A aortic dissection (SA-AoD) among patients admitted to our cardiovascular surgical service. A sinusoidal logistic regression model was used to analyze event data for 6081 calendar days. A cyclic peak risk for SA-AoD was observed for calendar day 304 (p=0.019). The odds ratios for the 3- and 6-month window surrounding this peak were 1.6 (p=0.054) and 1.7 (p=0.0040), respectively. Our results suggest than a seasonal variation exists in the incidence of SA-AoD.
在我们心血管外科接受治疗的患者中，斯坦福A型主动脉夹层（SA-AoD）的发病率存在季节性变化。采用正弦逻辑回归模型分析6081个日历日的事件数据。观察到SA-AoD在日历日304出现周期性高峰风险（p=0.019）。围绕该高峰的3个月和6个月窗口期的优势比分别为1.6（p=0.054）和1.7（p=0.0040）。我们的结果表明，SA-AoD的发病率存在季节性变化。
