Graduate School of Public Health, Shizuoka Graduate University of Public Health, Shizuoka, Japan.
Department of Nursing, Shizuoka City Shizuoka Hospital, Shizuoka, Japan.
PLoS One. 2024 Oct 11;19(10):e0311489. doi: 10.1371/journal.pone.0311489. eCollection 2024.
Several factors influence the onset of acute aortic dissection (AAD). However, few studies have examined AAD onset, weather conditions, and meteorological factors in Japan. This study aimed to identify meteorological factors associated with the onset of AAD in Japan. In this self-controlled study, patients diagnosed with AAD onset from May 1, 2012, to April 30, 2021, at Shizuoka City Shizuoka Hospital (Shizuoka, Japan) were included. Meteorological data from the Shizuoka District Meteorological Office were used. Control days were randomly selected from a 29-day period centered on the day of onset. Conditional logistic regression models were used to obtain odds ratios (ORs) and 95% confidence intervals (CIs) for the onset of AAD relative to the control day due to changes in meteorological factors. In total, 538 patients were included. The meteorological factors associated with the onset of AAD were identified as the daily mean temperature (OR = 1.10; 95% CI = 1.04-1.16), daily minimum temperature (OR = 1.09; 95% CI = 1.03-1.14), daily maximum temperature (OR = 1.05; 95% CI = 1.00-1.10), and the mean of the daily mean temperatures for the previous 7 days (OR = 1.17; 95% CI = 1.07-1.28) with a 1°C decrease in the temperature. The results of this study are expected to help raise awareness in clinical practice and among the general public about the increased risk of AAD associated with a drop in temperature.
多种因素会影响急性主动脉夹层（AAD）的发病。然而，针对日本 AAD 发病、天气条件和气象因素的研究较少。本研究旨在确定与日本 AAD 发病相关的气象因素。在这项自身对照研究中，纳入了 2012 年 5 月 1 日至 2021 年 4 月 30 日期间在日本静冈市静冈医院（静冈市）确诊为 AAD 发病的患者。气象数据来自静冈地区气象办公室。对照日是从发病日为中心的 29 天内随机选择的。使用条件逻辑回归模型获得气象因素变化与对照日相比 AAD 发病的优势比（OR）和 95%置信区间（CI）。共纳入 538 例患者。与 AAD 发病相关的气象因素有日平均气温（OR=1.10；95%CI=1.04-1.16）、日最低气温（OR=1.09；95%CI=1.03-1.14）、日最高气温（OR=1.05；95%CI=1.00-1.10）和前 7 天日平均气温的平均值（OR=1.17；95%CI=1.07-1.28），每降低 1°C。本研究的结果有望帮助提高临床实践和公众对与温度下降相关的 AAD 发病风险增加的认识。
