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小儿门诊手术中髂腹股沟/髂腹下神经阻滞与静脉注射吗啡用于控制睾丸固定术后疼痛的比较

Comparison of ilioinguinal/iliohypogastric nerve blocks and intravenous morphine for control of post-orchidopexy pain in pediatric ambulatory surgery.

作者信息

Al-Zaben Khaled R, Qudaisat Ibraheem Y, Abu-Halaweh Sami A, Zuabi Walid S, Al-Momani Hashem M, Albsoul Nader M, Khatib Faisal A

出版信息

Middle East J Anaesthesiol. 2014 Feb;22(4):393-8.

Abstract

BACKGROUND

The present study is a prospective randomized double-blinded study that designed to evaluate and compare the effectiveness of postoperative pain control and incidence of complications between ilioinguinal/iliohypogastric nerve block and intravenous morphine in paediatric patients undergoing unilateral orchidopexy in day surgery unit.

METHODS

Seventy patients aged 2-12 years were randomly allocated to two groups of thirty five. One group received intravenous morphine 100 microgram/kg before skin incision and the other group had ilioinguinal/iliohypogastric nerve block with 0.25 ml/kg bupivacaine 0.5% also before skin incision. All patients have received standardized anaesthesia. Postoperative pain was assessed using 0 - 10 scale at 0, 1, 2, 3 and 4 postoperative hours, also the intraoperative fentanyl requirements, time to first postoperative analgesia, the total number of paracetamol doses and any extra analgesic requirements were recorded, side effects like respiratory depression, vomiting, itching, inguinal hematoma and lower limb weakness were assessed during the first 24 hours.

RESULTS

Pain scores were significantly lower in the morphine group compared to the block group on admission and one hour after admission to the postanaesthesia care unit, no significant difference in pain score on 2nd, 3rd and 4th postoperative hours. The total number of intraoperative fentanyl doses was significantly higher in the block group compared to morphine group, there was no significant difference in the duration of analgesia, number of total paracetamol doses, need for extra analgesics in both groups over the 24 postoperative hours. None of the seventy patients experienced postoperative respiratory depression, inguinal hematoma or lower limb weakness, but significantly more patients in morphine group experienced vomiting and itching compared to the block group.

CONCLUSION

Ilioinguinal/iliohypogastric nerve block and intravenous morphine administered following general anaesthesia for unilateral orchidopexy in day surgery unit are safe and effective in controlling postoperative pain, morphine analgesia had a higher incidence of postoperative vomiting and itching.

摘要

背景

本研究是一项前瞻性随机双盲研究,旨在评估和比较小儿日间手术单元行单侧睾丸固定术时,髂腹股沟/髂腹下神经阻滞与静脉注射吗啡在术后疼痛控制效果及并发症发生率方面的差异。

方法

70例2至12岁患儿被随机分为两组,每组35例。一组在皮肤切开前静脉注射吗啡100微克/千克,另一组在皮肤切开前用0.5%布比卡因0.25毫升/千克行髂腹股沟/髂腹下神经阻滞。所有患者均接受标准化麻醉。术后0、1、2、3和4小时采用0至10分制评估疼痛,记录术中芬太尼用量、首次术后镇痛时间、对乙酰氨基酚总剂量及任何额外镇痛需求,在术后24小时内评估呼吸抑制、呕吐、瘙痒、腹股沟血肿及下肢无力等副作用。

结果

在进入麻醉后护理单元时及进入后1小时,吗啡组疼痛评分显著低于阻滞组,术后第2、3和4小时疼痛评分无显著差异。阻滞组术中芬太尼总剂量显著高于吗啡组,两组术后24小时镇痛持续时间、对乙酰氨基酚总剂量、额外镇痛需求无显著差异。70例患者均未出现术后呼吸抑制、腹股沟血肿或下肢无力,但吗啡组呕吐和瘙痒的患者明显多于阻滞组。

结论

小儿日间手术单元行单侧睾丸固定术全身麻醉后,髂腹股沟/髂腹下神经阻滞和静脉注射吗啡在控制术后疼痛方面安全有效,吗啡镇痛术后呕吐和瘙痒发生率较高。

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