一种用于检测蛋白质和核酸的灵敏表面增强拉曼光谱检测方法，该方法使用三螺旋分子开关进行级联信号放大。
A sensitive SERS assay for detecting proteins and nucleic acids using a triple-helix molecular switch for cascade signal amplification.
作者信息
Ye Sujuan, Wu Yanying, Zhang Wen, Li Na, Tang Bo
机构信息
College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, P. R. China.
出版信息
Chem Commun (Camb). 2014 Aug 25;50(66):9409-12. doi: 10.1039/c4cc03988b.
PMID:25008312
Abstract
A novel surface-enhanced Raman scattering (SERS) detection system is developed for proteins and nucleic acids based on a triple-helix molecular switch for multiple cycle signal amplification, achieving high sensitivity, universality, rapid analysis, and high selectivity.
摘要
基于三螺旋分子开关用于多循环信号放大，开发了一种用于蛋白质和核酸的新型表面增强拉曼散射（SERS）检测系统，实现了高灵敏度、通用性、快速分析和高选择性。
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