Borschel Marlene W, Choe Yong S, Kajzer Janice A
Abbott Nutrition, Abbott Laboratories, Columbus, OH, USA
Abbott Nutrition, Abbott Laboratories, Columbus, OH, USA.
Clin Pediatr (Phila). 2014 Dec;53(14):1375-82. doi: 10.1177/0009922814541804. Epub 2014 Jul 8.
Partially hydrolyzed formulas (pHF) represent a significant percentage of the infant formula market. A new whey-based, palm olein oil (PO)-free pHF was developed and a masked, randomized, parallel growth study was conducted in infants fed this formula or a commercially available whey-based pHF with PO. Infants between 0 and 8 days were to be enrolled and studied to 119 days of age. Growth and tolerance of infants were evaluated. Mean weight gain from 14 to 119 days of age was similar between groups. There were no significant differences between groups in weight, length, head circumference (HC), or length or HC gains. Infants fed the new PO-free pHF had significantly softer stools than those fed the PO-containing formula except at 119 days of age. This study demonstrates that whereas growth of infants fed different formulas during the first 4 months of life may be similar, infants may tolerate individual formulas differently.
部分水解配方奶粉（pHF）在婴儿配方奶粉市场中占很大比例。一种新的以乳清为基础、不含棕榈油精（PO）的pHF被研发出来，并对食用这种配方奶粉或市售含PO的乳清基pHF的婴儿进行了一项设盲、随机、平行生长研究。0至8天的婴儿被纳入研究，并随访至119日龄。评估了婴儿的生长和耐受性。两组婴儿在14至119日龄期间的平均体重增加相似。两组在体重、身长、头围（HC）或身长或HC增加方面无显著差异。除了在119日龄时，食用新的不含PO的pHF的婴儿的粪便明显比食用含PO配方奶粉的婴儿的粪便更软。这项研究表明，虽然在生命的前4个月中，食用不同配方奶粉的婴儿生长情况可能相似，但婴儿对不同配方奶粉的耐受性可能不同。
