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龈颊沟上鳞状细胞癌:203 例 11 年机构经验。

Squamous cell carcinoma of the superior gingivobuccal sulcus: an 11-year institutional experience of 203 cases.

机构信息

Department of Surgical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Delhi

Department of Surgical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Delhi.

出版信息

Jpn J Clin Oncol. 2014 Sep;44(9):807-11. doi: 10.1093/jjco/hyu088. Epub 2014 Jul 9.

DOI:10.1093/jjco/hyu088
PMID:25009221
Abstract

OBJECTIVE

The report presents an 11-year Institutional experience of 203 cases with superior gingivobuccal sulcus tumours receiving surgical intervention at a comprehensive tertiary cancer care centre.

METHODS

A retrospective chart review of patients with a confirmed diagnosis of squamous cell carcinoma of superior gingivobuccal sulcus was done and data related to patient demographic profile; details of surgical procedure, follow-up and survival were collected.

RESULTS

Infratemporal fossa clearance was performed in 56 patients. The 10-year overall survival and disease-free survival was observed to be 39 and 52%, respectively, with a median follow-up of 15 months. The overall survival was 40 and 36%, respectively, in cases with and without infratemporal fossa clearance. Similarly, the disease-free survival was found to be 58 and 49%, respectively, in cases with and without infratemporal fossa clearance.

CONCLUSION

Patients with higher stage tumours who underwent infratemporal fossa clearance showed better overall and disease-free survival than those who did not undergo infratemporal fossa clearance.

摘要

目的

报告了一家综合性三级癌症治疗中心对 203 例上颌龈颊沟肿瘤患者进行手术干预的 11 年机构经验。

方法

对确诊为上颌龈颊沟鳞状细胞癌的患者进行回顾性图表审查,并收集与患者人口统计学特征、手术程序、随访和生存数据相关的信息。

结果

56 例患者行颞下窝清扫术。10 年总生存率和无病生存率分别为 39%和 52%,中位随访时间为 15 个月。有和没有颞下窝清扫术的患者的总生存率分别为 40%和 36%。同样,有和没有颞下窝清扫术的患者的无病生存率分别为 58%和 49%。

结论

接受颞下窝清扫术的高分期肿瘤患者的总生存率和无病生存率优于未接受颞下窝清扫术的患者。

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