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口腔和口咽癌:流行病学与生存分析

Oral and oropharyngeal cancer: epidemiology and survival analysis.

作者信息

Moro Juliana da Silva, Maroneze Marília Cunha, Ardenghi Thiago Machado, Barin Luisa Machado, Danesi Cristiane Cademartori

机构信息

Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.

出版信息

Einstein (Sao Paulo). 2018 Jun 7;16(2):eAO4248. doi: 10.1590/S1679-45082018AO4248.

DOI:10.1590/S1679-45082018AO4248
PMID:29898090
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5995547/
Abstract

OBJECTIVE

To evaluate the epidemiological profile and survival rate of oral and oropharyngeal cancer patients seen at a university hospital.

METHODS

A cross-sectional study was carried out by means of the pathological reports of patients with oral and oropharyngeal cancer, seen at a university hospital of the Southern Region, between January 2004 and December 2014. Information was collected on patients and tumors. The mortality rate was gathered from the patient death registry in the Mortality Information System. Data were analyzed using the Kaplan-Meier survival curve and the log-rank test to compare variables.

RESULTS

The 5- and 10-year survival rates were 42% and 38%, respectively. The anatomical location had a significant association with survival rate (p=0.001), with the rates were better in the lips (p=0.04), and worse in the oropharynx (p=0.03). There were no statistically significant differences between survival rates according to age, sex, ethnicity, schooling level and histologic grade.

CONCLUSION

The survival rates of oral and oropharyngeal cancer were and associated with the anatomical site of the tumor.

摘要

目的

评估在一家大学医院就诊的口腔和口咽癌患者的流行病学特征及生存率。

方法

通过对2004年1月至2014年12月期间在南部地区一家大学医院就诊的口腔和口咽癌患者的病理报告进行横断面研究。收集了患者和肿瘤的信息。死亡率从死亡信息系统中的患者死亡登记处获取。使用Kaplan-Meier生存曲线和对数秩检验分析数据以比较变量。

结果

5年和10年生存率分别为42%和38%。解剖部位与生存率有显著关联(p=0.001),唇部的生存率较好(p=0.04),口咽部的生存率较差(p=0.03)。根据年龄、性别、种族、受教育程度和组织学分级,生存率之间无统计学显著差异。

结论

口腔和口咽癌的生存率与肿瘤的解剖部位有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af79/5995547/d2f9bc99329a/1679-4508-eins-16-02-eAO4248-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af79/5995547/569729c2df2a/1679-4508-eins-16-02-eAO4248-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af79/5995547/d2f9bc99329a/1679-4508-eins-16-02-eAO4248-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af79/5995547/569729c2df2a/1679-4508-eins-16-02-eAO4248-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af79/5995547/d2f9bc99329a/1679-4508-eins-16-02-eAO4248-gf02.jpg

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