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用于兆伏级X射线放射治疗的由固体水或铅制成的组织补偿器。

Tissue compensators made of solid water or lead for megavoltage X-ray radiotherapy.

作者信息

Constantinou C, Harrington J C

机构信息

Radiation Oncology Department, Brockton Hospital, MA 02402.

出版信息

Med Dosim. 1989;14(1):41-7. doi: 10.1016/0958-3947(89)90137-4.

Abstract

Curvature of the body within the treatment field of a patient undergoing radiotherapy can result in a non-uniformity of the dose distribution within the tumor volume which, for a 20 cm X 20 cm field and 6 MV X-rays, could exceed 30% of the prescribed tumor dose. The use of bolus is usually not satisfactory as skin sparing is lost. The use of a compensator at the position of the block holder assembly attenuates the primary beam while not significantly effecting the scattered radiation in the patient's body. Consequently, the necessary compensator thickness depends on the type of material used, the field size, beam energy, and depth of the point of interest. Using a compensator with thickness equal to that of the missing tissue would result in significant underdosing of the tumor. In this paper, measurements of the necessary thickness of solid water and lead required to reduce the non-uniformity of dose on the central axis to within 3% of the prescribed dose are presented for 6 MV and 10 MV X-rays.

摘要

接受放射治疗患者的身体在治疗野内发生弯曲,会导致肿瘤体积内剂量分布不均匀,对于20 cm×20 cm的射野和6 MV X射线,这种不均匀性可能超过规定肿瘤剂量的30%。使用等效填充物通常效果不佳,因为会失去皮肤保护。在挡块固定装置位置使用补偿器可衰减原射线,同时对患者体内的散射辐射影响不大。因此,所需补偿器的厚度取决于所用材料的类型、射野大小、射线能量以及感兴趣点的深度。使用厚度与缺失组织相等的补偿器会导致肿瘤剂量明显不足。本文给出了针对6 MV和10 MV X射线,将中心轴上剂量不均匀性降低到规定剂量的3%以内所需的固体水和铅的厚度测量结果。

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