Niroomand-Rad A, Javedan K, Rodgers J E, Harter K W
Department of Radiation Medicine, Georgetown University Medical Center, Washington, DC 20007, USA.
Int J Radiat Oncol Biol Phys. 1997 Mar 1;37(4):935-40. doi: 10.1016/s0360-3016(96)00538-x.
To determine the effects of a lucite beam spoiler on the dose distribution to points inside and outside the primary beam for head and neck irradiation with a 10-MV photon beam.
Build-up and depth-dose measurements were performed with a parallel-plate ionization chamber for 5 x 5, 10 x 10, and 15 x 15-cm field sizes using lucite spoilers with two different thicknesses at two different lucite-to-skin distances (LSD) for a 10-MV x-ray beam. Corrections were applied to account for finite chamber size. Beam profiles and isodose curves were obtained at several depths using film dosimetry. Beam uniformity was determined from uniformity indices. Peripheral doses (PD) were measured at the surface and at 1.5- and 2.5-cm depths using film dosimetry and a parallel-plate ionization chamber. Measurement points were positioned at the edge of a 10 x 10-cm field and at distances extending to 5.0 cm away. The treatment planning data for the 10-MV x-ray beam were modified to account for the effects of the beam spoiler when treating head and neck patients.
The spoiler increased the surface and build-up dose and shifted the depth of maximum dose toward the surface. With a 10-MV x-ray beam and a 1.2-cm-thick lucite at 15 cm LSD, a build-up dose similar to a 6-MV x-ray beam was achieved. The beam uniformity was altered at shallow depths. The peripheral dose was enhanced particularly at the surface and at the points close to the beam edge. The effects of the beam spoiler on beam profile and PD were reduced with increasing depths.
The lucite spoiler allowed use of a 10-MV x-ray beam for head and neck treatment by yielding a build-up dose similar to that of a 6-MV x-ray beam while maintaining skin sparing. The increase in PD was at superficial depths and was reduced at points away from the edge; therefore, it is clinically nonsignificant. Spoiling the 10-MV x-ray beam resulted in treatment plans that maintained dose homogeneity without the consequence of increased skin reaction or treatment volume underdose for regions near the skin surface.
确定有机玻璃射束 spoiler 对 10MV 光子束头颈部照射时主射束内外各点剂量分布的影响。
使用平行板电离室,针对 5×5、10×10 和 15×15cm 的射野尺寸,在两种不同的有机玻璃 - 皮肤距离(LSD)下,采用两种不同厚度的有机玻璃 spoiler,对 10MV X 射线束进行剂量建成和深度剂量测量。对有限电离室尺寸进行了校正。使用胶片剂量测定法在几个深度处获得射束轮廓和等剂量曲线。根据均匀性指数确定射束均匀性。使用胶片剂量测定法和平行板电离室在表面以及 1.5cm 和 2.5cm 深度处测量周边剂量(PD)。测量点位于 10×10cm 射野的边缘以及延伸至 5.0cm 远处。在对头颈部患者进行治疗时,对 10MV X 射线束的治疗计划数据进行了修正,以考虑射束 spoiler 的影响。
spoiler 增加了表面剂量和剂量建成,并使最大剂量深度向表面移动。对于 10MV X 射线束以及在 15cm LSD 处使用 1.2cm 厚的有机玻璃,实现了与 6MV X 射线束相似的剂量建成。在浅深度处射束均匀性发生了改变。周边剂量尤其在表面和靠近射束边缘的点处增强。随着深度增加,射束 spoiler 对射束轮廓和 PD 的影响减小。
有机玻璃 spoiler 通过产生与 6MV X 射线束相似的剂量建成,同时保持皮肤受量较低,使得能够使用 10MV X 射线束进行头颈部治疗。周边剂量的增加发生在浅表深度,在远离边缘的点处减小;因此,在临床上无显著意义。对 10MV X 射线束进行spoiling 处理后得到的治疗计划能够保持剂量均匀性,而不会导致皮肤反应增加或皮肤表面附近区域治疗体积剂量不足。