Department of Cognitive Science, ARC Centre of Excellence in Cognition and its Disorders, Macquarie University Sydney, NSW, Australia ; Department of Cognitive Science, Perception in Action Research Centre, Macquarie University Sydney, NSW, Australia.
Department of Cognitive Science, ARC Centre of Excellence in Cognition and its Disorders, Macquarie University Sydney, NSW, Australia.
Front Hum Neurosci. 2014 Jun 25;8:467. doi: 10.3389/fnhum.2014.00467. eCollection 2014.
The fluent production of speech requires accurately timed movements. In this article, we propose that a deficit in brain timing networks is one of the core neurophysiological deficits in stuttering. We first discuss the experimental evidence supporting the involvement of the basal ganglia and supplementary motor area (SMA) in stuttering and the involvement of the cerebellum as a possible mechanism for compensating for the neural deficits that underlie stuttering. Next, we outline the involvement of the right inferior frontal gyrus (IFG) as another putative compensatory locus in stuttering and suggest a role for this structure in an expanded core timing-network. Subsequently, we review behavioral studies of timing in people who stutter and examine their behavioral performance as compared to people who do not stutter. Finally, we highlight challenges to existing research and provide avenues for future research with specific hypotheses.
流畅的言语产生需要精确的时间控制。在本文中，我们提出，大脑时间网络的缺陷是口吃的核心神经生理缺陷之一。我们首先讨论支持口吃涉及基底节和辅助运动区（SMA）的实验证据，以及涉及小脑作为口吃潜在神经缺陷补偿机制的可能性。接下来，我们概述了右侧额下回（IFG）作为口吃的另一个潜在补偿部位，并提出了该结构在扩展核心时间网络中的作用。随后，我们回顾了口吃者时间知觉的行为研究，并将他们的行为表现与不口吃者进行了比较。最后，我们强调了现有研究的挑战，并提供了具有特定假设的未来研究途径。
