Mortimer J Y
Public Health Laboratory Service Communicable Disease Surveillance Centre, London, UK.
AIDS. 1989 Apr;3(4):199-207. doi: 10.1097/00002030-198904000-00002.
Tests for anti-HIV can be used (1) to establish for clinical or other reasons whether an individual has developed antibody to the virus, (2) to screen donated blood for evidence of infection and (3) to provide estimates of the prevalence of infection in a population. It is suggested that different testing strategies, using one or more distinct anti-HIV assays, are appropriate in these three situations. This paper examines the expected accuracy of the results that would arise if these strategies were implemented to test populations with various anti-HIV prevalences using assays with selected sensitivities and specificities. The expected outcomes are shown in tabular form for chosen values of the variables.
抗HIV检测可用于：（1）出于临床或其他原因确定个体是否已产生该病毒的抗体；（2）筛查献血以寻找感染证据；（3）估计人群中的感染流行率。建议在这三种情况下采用不同的检测策略，使用一种或多种不同的抗HIV检测方法。本文研究了如果采用这些策略，使用具有选定灵敏度和特异性的检测方法对不同抗HIV流行率的人群进行检测时，预期结果的准确性。对于选定的变量值，预期结果以表格形式呈现。
