Peuchmaur M, Emilie D, Vazeux R, Pons J C, Delfraissy J F, Lemaigre G, Galanaud P
Service de Pathologie, Hôpital A. Béclère, Paris, France.
AIDS. 1989 Apr;3(4):239-41. doi: 10.1097/00002030-198904000-00008.
Using immunohistochemical staining, in situ hybridization and a combination of both, we demonstrate here the replication of HIV in the endometrial stroma. Infected cells do not belong to the T-lymphocyte lineage but rather to a monocyte-macrophage cell type. This report suggests a possible relationship between HIV infection and endometritis. Moreover, HIV replication in endometrial tissues could play a role in heterosexual and materno-fetal transmission.
通过免疫组织化学染色、原位杂交以及两者结合的方法，我们在此证明了HIV在子宫内膜基质中的复制。被感染的细胞不属于T淋巴细胞谱系，而是属于单核细胞-巨噬细胞类型。本报告提示HIV感染与子宫内膜炎之间可能存在关联。此外，HIV在子宫内膜组织中的复制可能在异性传播和母婴传播中起作用。
