胎鼠肺Ⅱ型肺上皮细胞和成纤维细胞产生前列腺素。
Production of prostaglandins by fetal rat lung type II pneumonocytes and fibroblasts.
作者信息
Olson D M, Tanswell A K
机构信息
Department of Paediatrics, St. Joseph's Health Centre of London, University of Western Ontario, Canada.
出版信息
Biochim Biophys Acta. 1989 Jun 28;1003(3):327-30. doi: 10.1016/0005-2760(89)90240-3.
The output of prostaglandins I2, E2, F2 alpha and 13,14-dihydro-15-keto-PGF2 alpha (PGFM) from third passage day 20 rat fetal fibroblasts and type II alveolar pneumonocytes was studied. In 2 h incubations, the output levels for each cell type were: PGI2 greater than PGE2 much greater than PGF2 alpha = PGFM when cells were incubated with Ca2+ ionophore A23187 (10 microM) or arachidonic acid (1 microgram/ml).
对传代三次、培养20天的大鼠胎儿成纤维细胞和II型肺泡上皮细胞中前列腺素I2、E2、F2α和13,14-二氢-15-酮-PGF2α（PGFM）的生成情况进行了研究。在2小时的孵育过程中，当细胞与钙离子载体A23187（10微摩尔）或花生四烯酸（1微克/毫升）一起孵育时，每种细胞类型的生成水平为：PGI2＞PGE2＞＞PGF2α = PGFM。
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